Background: To investigate the compliance to self-monitoring of blood glucose (SMBG) among patients with type 2 diabetes mellitus (T2DM) and its influential factors.
Methods:The real-world SMBG use over 90 days among 415 T2DM patients were recorded by using a blood glucose monitoring platform (TDF-I, Tencent, China). Clinical features including age, sex, duration of diabetes, insulin treatment or not, and use of oral antidiabetic drugs were collected. Poor compliance was defined as the average frequency of weekly SMBG use over 90 days was below the criteria established by the physicians, and otherwise the patients were regarded as with good compliance. Factors affecting the SMBG compliance were analyzed by using independent sample t-test, Mann-Whitney U test, and multivariate logistic regression analysis.Results: Only 57.6% of patients in the study cohort had good compliance to SMBG. Multivariate logistic regression models showed that only the duration of T2DM and the use of oral antidiabetic agents were independently associated with SMBG compliance; more specifically, patients with longer course of disease had poorer SMBG compliance, and those had used oral antidiabetic agents had poorer SMBG compliance.Conclusions: SMBG compliance in T2DM patients needs to be further improved. For patients with a longer course of disease and/or under oral antidiabetic medication, interventions such as patient education should be adopted to increase the SMBG compliance.Keywords: Type 2 diabetes mellitus (T2DM); self-monitoring of blood glucose (SMBG); compliance; crosssectional study; real world study 87-91% of all diagnosed cases of diabetes. Diabetes kills over 5 million people every year, and most of them died of diabetic complications (3). Some studies including the UK Prospective Diabetes Study (UKPDS) and the Diabetes Control and Complications Trial (DCCT) have confirmed that good blood sugar control could effectively reduce the risk of diabetic complications (4,5). Thus, blood glucose monitoring has become essential for evaluating diabetic patients, developing a reasonable hypoglycemic regimen, reflecting the effectiveness of hypoglycemic treatment, and guiding treatment adjustment. Self-monitoring of blood glucose (SMBG) has been recommended for all diabetic patients in guidelines released by IDF, American Diabetes Association (ADA), and many other organizations (6,7).Studies have revealed that SMBG can significantly improve metabolic control in T2DM patients and may reduce diabetes-related endpoint events (6,8). However, the SMBG implementation is far from satisfactory worldwide. For instance, the International Diabetes Management Practices Study (IDMPS) found that the rate of SMBG use was only 29.7%, 35.7%, and 38.5% among T2DM patients in Asia, Eastern Europe, and Latin America (9). Patients' SMBG compliance is an important factor in determining the performance of SMBG. Thus, it is particularly important to identify the patients' SMBG compliance and its influential factors. Although a number of previous studies have...