Multifaceted approach to reducing preventable adverse drug events

Silverman, Jon; Stapinski, Carl; Churchill, William; Neppl, Camilla; Bates, David W.; Gandhi, Tejal K.

doi:10.1093/ajhp/60.6.582

Cited by 19 publications

(6 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The drug safety pharmacist can make clinical recommendations to physicians or pharmacists working in conjunction with physicians. Silverman et al 15 reported that 78% of such recommendations based on real time ADE monitoring were accepted and resulted in changes in medication orders. Schiff and colleagues 23 have also suggested a framework for multiple ways to link laboratory and pharmacy data.…”

Section: Discussionmentioning

confidence: 99%

Adverse drug events and medication errors: detection and classification methods

Morimoto

Gandhi²,

Seger³

et al. 2004

Quality and Safety in Health Care

260

277

View full text Add to dashboard Cite

Investigating the incidence, type, and preventability of adverse drug events (ADEs) and medication errors is crucial to improving the quality of health care delivery. ADEs, potential ADEs, and medication errors can be collected by extraction from practice data, solicitation of incidents from health professionals, and patient surveys. Practice data include charts, laboratory, prescription data, and administrative databases, and can be reviewed manually or screened by computer systems to identify signals. Research nurses, pharmacists, or research assistants review these signals, and those that are likely to represent an ADE or medication error are presented to reviewers who independently categorize them into ADEs, potential ADEs, medication errors, or exclusions. These incidents are also classified according to preventability, ameliorability, disability, severity, stage, and responsible person. These classifications, as well as the initial selection of incidents, have been evaluated for agreement between reviewers and the level of agreement found ranged from satisfactory to excellent (kappa = 0.32-0.98). The method of ADE and medication error detection and classification described is feasible and has good reliability. It can be used in various clinical settings to measure and improve medication safety.

show abstract

Section: Discussionmentioning

confidence: 99%

Adverse drug events and medication errors: detection and classification methods

Morimoto

Gandhi²,

Seger³

et al. 2004

Quality and Safety in Health Care

260

277

View full text Add to dashboard Cite

show abstract

“…21 22 The triggers and text screening based on computerized systems can be a foundation for the development of an ADE monitor. 15 The possible incidents detected through such triggers are then evaluated by a drug safety pharmacist for actual or potential ADEs on a daily basis. The drug safety pharmacist can make clinical recommendations to physicians or pharmacists working in conjunction with physicians.…”

Section: Discussionmentioning

confidence: 99%

“…Triggers can also be used to monitor for ADEs and medication errors in daily practice once their discrimination ability is established. 15 Specific drugs, combinations of drugs, symptoms, ICD-9 related diagnoses, and laboratory results can all be used as triggers. These triggers from an EMR or CPOE are then reviewed by the research nurses, pharmacists, or research assistants and assessed as incidents or not.…”

Section: Data Reviewmentioning

confidence: 99%

Adverse drug events and medication errors: detection and classification methods

Morimoto

2004

Quality and Safety in Health Care

342

View full text Add to dashboard Cite

“…Em um hospital terciário dos Estados Unidos, a subcomissão de segurança no uso de medicamentos tem como principal responsabilidade reduzir os índices de eventos adversos preveníveis relacionados a medicamentos. Em 2001, a maioria das 44 recomendações elaboradas por essa subcomissão foram relacionadas à freqüência e ao intervalo entre a administração dos medicamentos, à descontinuidade da medicação, aos ajustes de doses em insuficiência renal, à necessidade de testes laboratoriais e à eliminação de duplicação da terapêutica (23).…”

Section: Experiências Internacionaisunclassified

Comissões farmacoterapêuticas no Brasil: aquém das diretrizes internacionais

Marques¹,

Zucchi²

2006

Rev Panam Salud Publica

View full text Add to dashboard Cite

The inadequate use of drugs leads to lack of therapeutic efficacy, adverse reactions, side effects, preventable drug interactions, increased bacterial resistance to antibiotics, and wasted resources. Changing this scenario is one of the most complex challenges facing health systems today. One approach used to rationalize the use of drugs lies in the creation of pharmacy and therapeutics committees, whose main role is to guide and assist health institutions at all levels in selecting drugs and monitoring their use, training professionals to use drugs rationally, and collecting systematized information to guide new strategies and actions. Brazil, unlike other parts of the world, does not make it compulsory to have pharmacy and therapeutics committees. Although committees for monitoring hospital infections are compulsory in that country, their action is restricted to hospitals and is not as broad as that proposed for pharmacy and therapeutics committees. Data from 2003 shows that among 250 public and private hospitals in Brazil, only 29 had pharmacy and therapeutics committees. It is essential that the need to make these committees compulsory at all levels of the Brazilian health system be discussed, and that the national Ministry of Health and other related agencies create the conditions necessary for the establishment of pharmacy and therapeutics committees, in accordance with other health policies currently in place.

show abstract

Multifaceted approach to reducing preventable adverse drug events

Cited by 19 publications

References 4 publications

Adverse drug events and medication errors: detection and classification methods

Adverse drug events and medication errors: detection and classification methods

Adverse drug events and medication errors: detection and classification methods

Comissões farmacoterapêuticas no Brasil: aquém das diretrizes internacionais

Contact Info

Product

Resources

About