Multielemental analysis of 18 essential and toxic elements in amniotic fluid samples by ICP-MS: Full procedure validation and estimation of measurement uncertainty

Markiewicz, Barbara; Sajnóg, Adam; Lorenc, Wiktor; Hańć, Anetta; Komorowicz, Izabela; Suliburska, Joanna; Kocyłowski, Rafał; Barałkiewicz, Danuta

doi:10.1016/j.talanta.2017.05.078

Cited by 26 publications

(20 citation statements)

References 23 publications

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“…Similarly, although we found no Cr in our samples, this finding could be in agreement with literature data where it was reported to be very low, between 2 and 3 ppb [26][27][28][29][30]. Interestingly, while no Cr was detected in the micro/submicro fraction, 13% of the patients had a concentration higher than the limit of blank in the nano/ion fraction.…”

Section: Discussionsupporting

confidence: 92%

“…Indeed, we found a mean Fe concentration of 434 ppb while it ranged from 466 to 536 ppb in different studies [26][27][28]. Similarly, Al concentration in amniotic fluids is reported to be between 131 and 159 ppb in the literature [26,[28][29][30], while we found a concentration of 141 ppb. For Cu [26,28,30], Ni [28,30] and Zn [26,28,30,31], although we did not find exactly the same concentration as in the literature, they were in the same order of magnitude.…”

Section: Discussionsupporting

confidence: 68%

“…Similarly, Al concentration in amniotic fluids is reported to be between 131 and 159 ppb in the literature [26,[28][29][30], while we found a concentration of 141 ppb. For Cu [26,28,30], Ni [28,30] and Zn [26,28,30,31], although we did not find exactly the same concentration as in the literature, they were in the same order of magnitude. Regarding Co, while it is reported that its concentration in amniotic fluid is about 0.2-0.5 ppb [26,[28][29][30][31] we found a patient with a concentration of 318 ppb.…”

Section: Discussionsupporting

confidence: 61%

“…For Cu [26,28,30], Ni [28,30] and Zn [26,28,30,31], although we did not find exactly the same concentration as in the literature, they were in the same order of magnitude. Regarding Co, while it is reported that its concentration in amniotic fluid is about 0.2-0.5 ppb [26,[28][29][30][31] we found a patient with a concentration of 318 ppb. Obviously, this result should be taken with care as it is only from one patient but it is consistent with data from Jalali and Koski [27] who found a Co concentration in amniotic fluid ranging from 26 to 366 ppb.…”

Section: Discussioncontrasting

confidence: 53%

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Elemental fingerprint of human amniotic fluids and relationship with potential sources of maternal exposure

Raia-Barjat

Prieux

Leclerc

et al. 2020

Journal of Trace Elements in Medicine and Biology

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Background-The impact of nanoparticles we are increasingly exposed to remains largely unknown. Of particular concern is the exposure of pregnant women and potential impact on fetal development. Indeed, many in vitro and in vivo animal studies have shown that nanoparticles are able to cross the placental barrier and induce toxic effects to the fetus. However, little is known in humans. Objective-The aim and originality of this study were to investigate the nanoparticle burden of amniotic fluids in pregnant women. Methods-To that purpose, 100 amniotic fluids collected for clinical purposes were used to determine the nanoparticle quantity and nature by inductively coupled plasma atomic emission spectroscopy (NAMIOTIC, ClinicalTrials.gov Identifier: NCT02720887). Results-The prevalence of patients with a substantial concentration for the essential trace elements Cu, Fe and Zn was high, while that of patients with a substantial concentration of Al, Ag, Be, Co, Cr, Ni, Si, Ti and W was relatively low (under 20%). It was generally higher in the fraction containing nanoparticles and ions than in the fraction containing micro-and submicroparticles. No correlation was found between the nanoparticle burden and the different potential sources of exposure to nanoparticles (smoking status of the patient, living area, heating source, mode of transport, leisure, use of hygiene products and cosmetics and occupational activities). Conclusion-Our results showing low concentrations and low prevalence of most of the assessed elements in amniotic fluids are reassuring. Further research is needed to draw firm conclusions on the developmental toxicity of engineered nanoparticles in humans but the present paper can provide a useful basis for further evaluation of the fetal toxicity of nanoparticles.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 68%

Section: Discussionsupporting

confidence: 61%

Section: Discussioncontrasting

confidence: 53%

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Elemental fingerprint of human amniotic fluids and relationship with potential sources of maternal exposure

Raia-Barjat

Prieux

Leclerc

et al. 2020

Journal of Trace Elements in Medicine and Biology

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“…Taking into account the literature data [27,28], an ICP-MS method and inductively coupled plasma optical emission spectrometry (ICP-OES) can be distinguished among other analytical techniques as a powerful tool in multielemental analysis in a wide range of concentrations, with high sensitivity, short time of analysis, and low limits of quantitation. Applications of ICP-MS and ICP-OES have been reported for the wide range of biological and clinical samples, both fluids (blood [29], amniotic fluid [30], and cerebrospinal fluid [31]) and solid tissues [31][32][33][34][35][36]. Complex matrices of clinical samples are often a source of interferences caused by monoatomic and polyatomic ions, formed in the plasma from the matrix constituents.…”

Section: Chemical Analysis Of Prostate Gland Elemental Contentmentioning

confidence: 99%

ICP-MS analysis of diet supplementation influence on the elemental content of rat prostate gland

et al. 2019

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Metabolism of numerous elements is involved in carcinogenesis. Among other, calcium and zinc metabolic pathways coincide with prostate cancer development. It is probable that the restoration of elemental loses can moderate or even stop prostate malignancy. For this reason, studies on elemental content in tissues taken from organisms with cancer are carried out to establish proper supplementation. ICP-MS is a well-established method for the analysis of such a kind of samples. The study aimed to investigate the influence of dietary supplementation on elemental content in the prostate gland of rats with implanted cancer cells. Tested animals were divided into six dietary groups: standard diet and supplementation with Ca, Fe, Zn, Cu, or Se. Every dietary group was divided into experimental group (with implanted cancer cells) and control group (without cancer cells). Prostate tissue was dried and treated with microwave-assisted mineral digestion. Total elemental content was quantified by ICP-MS. Student's t test and analysis of variance with post-hoc Tukey's procedure were applied to compare treatment and dietary groups. The total content of selected elements (K, Na, Mg, Ca, Fe, Zn, Cu, Sr, Pb, and Se) was quantified, with statistically significant differences in Na, Mg, Ca, Zn, Sr, and Se contents between treatment groups and in Ca, Fe, Cu, Zn, Sr, and Pb contents between diet groups. High heterogeneity within group could be observed for Zn content in the tissue, confirming the crucial role of zinc in prostate gland metabolism and pointing its inter-individual variability. Graphic abstractKeywords Alkali metals · Antitumor agents · Inductively coupled plasma mass spectrometry · Transition metal compounds * Agata Jagielska

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Multielement analysis of Zanthoxylum bungeanum Maxim. essential oil using ICP-MS/MS

Xie

Shi

2018

Anal Bioanal Chem

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The concentrations of trace elements (Cr, Ni, As, Cd, Hg, and Pb) in Zanthoxylum bungeanum Maxim. essential oil (ZBMEO) were determined by inductively coupled plasma tandem mass spectrometry. The ZBMEO sample was directly analyzed after simple dilution with n-hexane. Aiming for a relatively high vapor pressure of n-hexane and its resultant loading on plasma, we used a narrow injector torch and optimized plasma radio frequency power and carrier gas flow to ensure stable operation of the plasma. An optional gas flow of 20% O in Ar was added to the carrier gas to prevent the incomplete combustion of highly concentrated organic carbon in plasma and the deposition of carbon on the sampling and skimmer cone orifices. In tandem mass spectrometry mode, O was added to the collision/reaction cell to eliminate the interferences. The limits of detection for Cr, Ni, As, Cd, Hg, and Pb were 2.26, 1.64, 2.02, 1.35, 1.76, and 0.97 ng L, respectively. After determination of 23 ZBMEO samples from different regions in China, we found that the average concentration ranges of trace elements in the 23 ZBMEO samples were 0.72-6.02 ng g, 0.09-2.87 ng g, 0.21-5.84 ng g, 0.16-2.15 ng g, 0.13-0.92 ng g, and 0.17-0.73 ng g for Cr, Ni, As, Cd, Hg, and Pb, respectively. The trace elements in ZBMEO differed significantly when different extraction technologies were used. The study revealed that the contents of the toxic elements As, Cd, Hg, and Pb were extremely low, and hence they are unlikely to pose a health risk following ZBMEO ingestion. Graphical abstract The working mechanism of sample analysis by ICP-MS/MS.

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Multielemental analysis of 18 essential and toxic elements in amniotic fluid samples by ICP-MS: Full procedure validation and estimation of measurement uncertainty

Cited by 26 publications

References 23 publications

Elemental fingerprint of human amniotic fluids and relationship with potential sources of maternal exposure

Elemental fingerprint of human amniotic fluids and relationship with potential sources of maternal exposure

ICP-MS analysis of diet supplementation influence on the elemental content of rat prostate gland

Multielement analysis of Zanthoxylum bungeanum Maxim. essential oil using ICP-MS/MS

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