Multidrug-Resistant<i>Escherichia coli</i>in Bovine Animals, Europe

Brennan, Evan; Martins, Marta; McCusker, Matthew P.; Juan, Wang; Alves, Bruno Martins; Hurley, Daniel; Garch, Farid El; Woehrle, Frédérique; Miossec, Christine; McGrath, Leisha; Srikumar, Shabarinath; Wall, Patrick; Fanning, Séamus

doi:10.3201/eid2209.160140

Cited by 35 publications

(25 citation statements)

References 12 publications

(18 reference statements)

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“…However, the prevalence of mcr-1 in bacteria from dairy cattle remains low, ranging from 0.5% to 0.8% in China (He et al, 2017;Bai et al, 2018;Zheng et al, 2019), 2.6% in Egypt (Khalifa et al, 2016), and 0% in Brazil (Palmeira et al, 2018). Overall, there is a greater number of studies in cattle from European countries, including the Netherlands (Veldman et al, 2016), Germany (Falgenhauer et al, 2016), France (Brennan et al, 2016;Haenni et al, 2016;Lupo et al, 2018;Gay et al, 2019), Italy (Alba et al, 2018), Belgium (Malhotra-Kumar et al, 2016), Spain (Hernandez et al, 2017), and Portugal (Clemente et al, 2019), compared with Asian countries, where the majority of such studies comes from China (Wang et al, 2018b) and Japan (Suzuki et al, 2016;Kawanishi et al, 2017). However, levels of colistin resistance are consistently low.…”

Section: Prevalence Of Mcr Genes In Animals and Animalderived Food Prmentioning

confidence: 99%

Farm animals and aquaculture: significant reservoirs of mobile colistin resistance genes

Shen

Zhang

Schwarz

et al. 2020

Environmental Microbiology

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Summary Colistin resistance has attracted substantial attention after colistin was considered as a last‐resort drug for the treatment of infections caused by carbapenem‐resistant and/or multidrug‐resistant (MDR) Gram‐negative bacteria in clinical settings. However, with the discovery of highly mobile colistin resistance (mcr) genes, colistin resistance has become an increasingly urgent issue worldwide. Despite many reviews, which summarized the prevalence, mechanisms, and structures of these genes in bacteria of human and animal origin, studies on the prevalence of mobile colistin resistance genes in aquaculture and their transmission between animals and humans remain scarce. Herein, we review recent reports on the prevalence of colistin resistance genes in animals, especially wildlife and aquaculture, and their possibility of transmission to humans via the food chain. This review also gives some insights into the routine surveillance, changing policy and replacement of polymyxins by polymyxin derivatives, molecular inhibitors, and traditional Chinese medicine to tackle colistin resistance.

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Section: Prevalence Of Mcr Genes In Animals and Animalderived Food Prmentioning

confidence: 99%

Farm animals and aquaculture: significant reservoirs of mobile colistin resistance genes

Shen

Zhang

Schwarz

et al. 2020

Environmental Microbiology

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“…Escherichia coli Europe Germany Faecal (Wieler et al, 2011) Mastitis (Freitag et al, 2017;Michael et al, 2017) Diarrheic (Ewers et al, 2014) Sick (Michael et al, 2017) Infection (Brennan et al, 2016) Denmark Commensal (Kjeldsen et al, 2015) ND (Garcia-Fernandez et al, 2011;Jakobsen et al, 2015) Spain Mastitis (Briñas et al, 2005) Finland Faecal (P€ aiv€ arinta et al, 2016) France Faecal (Haenni et al, 2014;Hartmann et al, 2012;Madec et al, 2008;Meunier et al, 2006) Mastitis (Dahmen et al, 2013) Diarrheic (Hartmann et al, 2012) Sick (Madec et al, 2008;Valat et al, 2016) Infection (Meunier et al, 2006) Hungary Infection (Toth et al, 2013) Portugal Faecal (Ramos et al, 2013) Mayotte ND (Gay et al, 2018) Netherlands Faecal (Ceccarelli et al, 2019;Heuvelink et al, 2019;Hordijk et al, 2013a, b, c) United Kingdom…”

Section: Ctx-m-1mentioning

confidence: 99%

Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in cattle production – a threat around the world

Palmeira

Ferreira

2020

Heliyon

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Food producing animal is a global challenge in terms of antimicrobial resistance spread. Extended-spectrum betalactamase (ESBL)-producing Enterobacteriaceae are relevant opportunistic pathogens that may spread in many ecological niches of the One Health approach as human, animal and environment due to intestinal selection of antimicrobial resistant commensals in food production animals. Cattle production is a relevant ecological niche for selection of commensal bacteria with antimicrobial resistance from microbiota. Enterobacteriaceae show importance in terms of circulation of resistant-bacteria and antimicrobial resistance genes via food chain creating a resistance reservoir, setting up a threat for colonization of humans and consequent health risk. ESBL-producing Enterobacteriaceae are a threat in terms of human health responsible for life threatening outbreaks and silent enteric colonization of community populations namely the elder population. Food associated colonization is a risk difficult to handle and control. In a time of globalization of food trading, population intestinal colonization is a mirror of food production and in that sense this work aims to make a picture of ESBL-producing Enterobacteriaceae in animal production for food over the world in order to make some light in this reality of selection of resistant threats in food producing animal.

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“…In Europe, mcr-1 was reported in Germany (Brennan et al, 2016;Irrgang et al, 2016;Guenther et al, 2017) . Based on a retrospective survey in Germany, mcr-1 was found in 402 of 10,600 (3.79%) E. coli isolates from livestock and food (Irrgang et al, 2016).…”

Section: Livestockmentioning

confidence: 99%

“…, Belgium(Xavier et al, 2016a, b), Spain(Quesada et al, 2016), Italy(Carnevali et al, 2016), Portugal(Campos et al, 2016;Figueiredo et al, 2016;Hu et al, 2016;Tse and Yuen, 2016), France(Brennan et al, 2016;El Garch et al, 2017), The Netherlands(Kluytmans-van den Bergh et al, 2016;Veldman et al, 2016), Estonia(Brauer et al, 2016), Great Britain(Anjum et al, 2016), Lithunia, Wallonia and Flanders(Malhotra-Kumar et al, 2016)…”

mentioning

confidence: 99%

Plasmid-mediated colistin resistance in animals: current status and future directions

Sun

Zeng

et al. 2017

Anim. Health. Res. Rev.

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Colistin, a peptide antibiotic belonging to the polymyxin family, is one of the last effective drugs for the treatment of multidrug resistant Gram-negative infections. Recent discovery of a novel mobile colistin resistance gene, mcr-1, from people and food animals has caused a significant public health concern and drawn worldwide attention. Extensive usage of colistin in food animals has been proposed as a major driving force for the emergence and transmission of mcr-1; thus, there is a worldwide trend to limit colistin usage in animal production. However, despite lack of colistin usage in food animals in the USA, mcr-1-positive Escherichia coli isolates were still isolated from swine. In this paper, we provided an overview of colistin usage and epidemiology of mcr-1 in food animals, and summarized the current status of mechanistic and evolutionary studies of the plasmid-mediated colistin resistance. Based on published information, we further discussed several non-colistin usage risk factors that may contribute to the persistence, transmission, and emergence of colistin resistance in an animal production system. Filling the knowledge gaps identified in this review is critical for risk assessment and risk management of colistin resistance, which will facilitate proactive and effective strategies to mitigate colistin resistance in future animal production systems.

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Multidrug-ResistantEscherichia coliin Bovine Animals, Europe

Cited by 35 publications

References 12 publications

Farm animals and aquaculture: significant reservoirs of mobile colistin resistance genes

Farm animals and aquaculture: significant reservoirs of mobile colistin resistance genes

Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in cattle production – a threat around the world

Plasmid-mediated colistin resistance in animals: current status and future directions

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