Multidisciplinary Rehabilitation in Amyotrophic Lateral Sclerosis

Ng, Louisa; Khan, Fary

doi:10.5772/31774

Cited by 5 publications

(2 citation statements)

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“…There are currently few if any treatment options, early detection or prevention methods are not yet available, and rehabilitation treatments addressing specific needs and deficits are the most frequent form of therapy available to most of ALS patients 4 . However, rehabilitation results vary due to the complexity of ALS, broad spectrum of presentation and disease progression rate, and development of individualized, complex rehabilitation protocols is recommended [5][6][7][8][9] .…”

Section: Introductionmentioning

confidence: 99%

Complex Treatment of Amyotrophic Lateral Sclerosis Patient

Białkowska

Mroczkowska

Huflejt

et al. 2019

ACC

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Amyotrophic lateral sclerosis is a progressive and fatal degenerative neuromuscular disease with few if any treatment options and physical rehabilitation addressing specific deficits is the most frequent form of therapy. Patients also suffer from depression and increased anxiety. Our purpose was to assess the neurorehabilitation effectiveness in a patient with amyotrophic lateral sclerosis who underwent stem cell transplantation but refused physiotherapy due to depression. Disease progression was followed using the revised Amyotrophic Lateral Sclerosis Functional Rating Scale bimonthly for six months pre-and then post-stem cell transplantation. Psychological traits were assessed using six standardized tests. Quantitative electroencephalogram diagnostics was performed before the first and after the last neurofeedback session, and sessions were conducted on a 3-times-a-week basis. The physiotherapy protocol included proprioceptive neuromuscular facilitation, electrical modalities unit applied to the lumbar spine area, and breathing, relaxation and walking exercises, among others. Increased motivation and marked decrease in the pain level was associated with the patient's willingness to complete physiotherapy, which resulted in improvements in most neuromuscular deficits and in increased respiratory capacity. During the 12 post-rehabilitation months, progression of the disease decelerated, and a positive behavioral change was noted. The study suggested that neurofeedback could be used as a neurorehabilitation component of the personalized complex rehabilitation protocol in patients with amyotrophic lateral sclerosis.

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Section: Introductionmentioning

confidence: 99%

Complex Treatment of Amyotrophic Lateral Sclerosis Patient

Białkowska

Mroczkowska

Huflejt

et al. 2019

ACC

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“…Defining Amyotrophic Lateral Sclerosis (ALS) as the “most common chronic neurodegenerative disorder of the motor system in adults,” Ng and Khan stated that this disorder is a rare disease with a range of 0.0015 to 0.0025% throughout the world, with more men afflicted than women (the ratio of men to women was estimated to be 1.5) ( 1 ). They classified the symptoms as fatigue and depression, which impact on physical conditions.…”

Section: Introductionmentioning

confidence: 99%

Fatigue and Depression in Iranian Amyotrophic Lateral Sclerosis Patients in Tehran in 2012

et al. 2016

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IntroductionAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a progressive and rapid course. Fatigue and depression are common among ALS patients. The aim of this study was to determine the relationship between depression and fatigue in Iranian ALS patients.MethodsIn this 2012 cross-sectional study, 40 ALS patients, including 22 females and 18 males, were selected through consecutive relapsing-remitting, and 40 age- and gender-matched health controls (HCs) were recruited from Loghman Hakim Hospital in Tehran, Iran. The Persian version of the Fatigue Severity Scale (FSS-Per) questionnaire and depression substance of Hospital Anxiety and Depression Scale (HADS) were used to assess fatigue and depression. Data were analyzed using the Kolmogorov-Sminov Test, Levene’s test, Independent Samples t-test, and Pearson product-moment correlation coefficient.ResultsWe identified a significant and positive relationship between fatigue and depression in patients with ALS (p=0.000). Furthermore, the scores of fatigue and depression in ALS patients were higher than in non-ALS patients.ConclusionThe results indicated that there was a relationship between fatigue and depression in ALS patients and that early intervention services can improve these symptoms. Further studies are suggested to investigate the direction of such relationship.

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