Multicomponent Click Synthesis of New 1,2,3-Triazole Derivatives of Pyrimidine Nucleobases: Promising Acidic Corrosion Inhibitors for Steel

González-Olvera, Rodrigo; Espinoza-Vázquez, Araceli; Negrón‐Silva, Guillermo E.; Palomar-Pardavé, M.; Romero-Romo, M.; Santillán, Rosa

doi:10.3390/molecules181215064

Cited by 50 publications

(30 citation statements)

References 61 publications

(80 reference statements)

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“…The impedance technique can provide more detailed information about the interfacial properties of surface-modified electrodes [35]. In this experiment, two methods of CV and electrochemical impedance spectroscopy (EIS) were used to monitor the fabricating process of the modified electrode, and the results are presented in Fig.…”

Section: Electrochemical Property Of Cs@al 2 O 3 @Go Film-modified Gcementioning

confidence: 99%

Synthesis of graphene oxide-wrapped core–shell structured carbon sphere@Al2O3 as electrode material for voltammetric determination of butylated hydroxyanisole in food products

Gan

Shi

et al. 2015

Ionics

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Here, we report a graphene oxide-wrapped coreshell structured carbon sphere@Al 2 O 3 composite (CS@Al 2 O 3 @GO) as the electrode material for sensitive determination of butylated hydroxyanisole (BHA). The coreshell structured CS@Al 2 O 3 was synthesized through a solution-based approach by using glucose and metal salts as precursors via a simple one-pot hydrothermal synthesis. Then, the CS@Al 2 O 3 was amino-functionalized and wrapped by conductive graphene oxide (GO) sheets through the electrostatic interaction. As a result, the CS@Al 2 O 3 @GO endowed the modified electrode fast electron transfer rate and high electrocatalytic activity toward BHA oxidation. Under the optimal conditions, the oxidation current increased linearly with the concentration of BHA in the range of 0.2~200 μM with the detection limit and quantification limit of 41 and 136.7 nM using differential pulse voltammetry. The presented method was also demonstrated for the determination of BHA in food samples with satisfactory results.

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Section: Electrochemical Property Of Cs@al 2 O 3 @Go Film-modified Gcementioning

confidence: 99%

Synthesis of graphene oxide-wrapped core–shell structured carbon sphere@Al2O3 as electrode material for voltammetric determination of butylated hydroxyanisole in food products

Gan

Shi

et al. 2015

Ionics

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“…A new 1,2,3‐triazole derivative of pyrimidine nucleobases was reported via a Cu(I)‐catalysed one‐pot three‐component click reaction involving 1,3‐dipolar cycloadditon with N‐1 propargylpyrimidine nucleobases (Scheme ) . The reaction involved monopropargyl nucleobases, sodium azide and several benzyl halides in presence of Cu(OAc) 2 ⋅ H 2 O in EtOH/H 2 O (2 : 1 v/v) at room temperature for 24 h to afford 1,4‐disubstituted 1,2,3‐triazole nucleobases.…”

Section: Synthesis Of Heterocyclesmentioning

confidence: 99%

Copper‐Catalysed Multicomponent Syntheses of Heterocycles

Cherian¹,

Harry²,

Saranya³

et al. 2019

Asian J Org Chem

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Heterocycles cover a wide range of organic compounds and are ubiquitous in different areas of life sciences and technology. Multicomponent syntheses of heterocycles are very advantageous in comparison with the classical methods of heterocycle synthesis. In this review, copper-catalysed multicomponent reactions used for the synthesis of heterocycles published between 2004 and 2018 are summarised.[a] R. Scheme 1. Synthesis of 2-iminooxetanes and maleimides by Cu-catalysed three-component reaction and ring expansion respectively.

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“…Bonnamour et al have reported a consecutive threecomponent synthesis of trifluoromethyltriazole derivatives 22 as pseudopeptide based upon this concept (Scheme 14). [59,60] The concept of in situ azide generation has also been employed for the generation of 8-trifluoromethylquinoline-based 1,2,3-triazoles derivatives 25 for the evaluation of their in vitro antimicrobial activity. [54] CF 3 -containing derivatives, modifying the biological activity of a system, [55] have acquired significance, particularly in the field of peptidomimetics.…”

Section: Azide Formation Via Nucleophilic Aliphatic Substitutionmentioning

confidence: 99%

Multicomponent Syntheses based upon Copper‐Catalyzed Alkyne‐Azide Cycloaddition

2015

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The copper-catalyzed alkyne-azide cycloaddition (CuAAC) is a highly versatile, regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles under mild reaction conditions and has found numerous applications in medicinal, bioorganic, and materials chemistry in the past one and a half decades. By virtue of the enormous tolerance for functional groups and the mild reaction conditions, CuAAC has become increasingly important in combination with multicomponent reactions (MCR), either in a domino or in a consecutive fashion. While the majority of CuAAC-based MCR are founded on the in situ or en route generation of azides, one-pot generation of alkynes and the concatenation with other MCR are rapidly catching up and novel sequences for efficient one-pot syntheses of triazole-based structures in a multicomponent fashion are constantly evolving. This review summarizes important contributions of CuAAC-based MCR including MCRtype applications in polymer science.

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Multicomponent Click Synthesis of New 1,2,3-Triazole Derivatives of Pyrimidine Nucleobases: Promising Acidic Corrosion Inhibitors for Steel

Cited by 50 publications

References 61 publications

Synthesis of graphene oxide-wrapped core–shell structured carbon sphere@Al2O3 as electrode material for voltammetric determination of butylated hydroxyanisole in food products

Synthesis of graphene oxide-wrapped core–shell structured carbon sphere@Al2O3 as electrode material for voltammetric determination of butylated hydroxyanisole in food products

Copper‐Catalysed Multicomponent Syntheses of Heterocycles

Multicomponent Syntheses based upon Copper‐Catalyzed Alkyne‐Azide Cycloaddition

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