Multichannel Stimulation of Phrenic Nerves by Epineural Electrodes

Mayr, Winfried; Bijak, Michaela; Girsch, Werner; HOLLE, JUURGEN; LANMUULLER, HERMANN; Thoma, H.; Zrunek, M.

doi:10.1097/00002480-199307000-00118

Cited by 10 publications

(16 citation statements)

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“…The active electrodes are changed for each impulse, and the stimulation frequency decreases from 25 to 16 Hz during the inspiration burst. The Vienna (Austria) group implements carousel stimulation ( 5). The active electrodes are changed after each inspiration burst, and a constant stimulation frequency of 26 Hz is used.…”

Section: Resultsmentioning

confidence: 99%

“…Nerve pacing is effected by ring shaped stainless steel electrodes. These epineurial electrodes are used clinically in the Vienna phrenic pacemaker ( 5).…”

Section: Methodsmentioning

confidence: 99%

“…In developing the stimulator, we had set ourselves the following goals. First, the system should allow the implementation of all stimulation techniques used to date in diaphragm pacing in humans (single channel or multichannel methods such as carousel stimulation [5] and sequential stimulation [6]). Second, the use of external devices should be limited to the time necessary for programming to maximize the patient's freedom of movement.…”

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confidence: 99%

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Battery‐Powered Implantable Nerve Stimulator for Chronic Activation of Two Skeletal Muscles Using Multichannel Techniques

et al. 1999

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Chronic activation of skeletal muscle is used clinically in representative numbers for diaphragm pacing to restore breathing and for dynamic graciloplasty to achieve fecal continence. The 3 different stimulation techniques currently used for electrophrenic respiration (EPR) all apply high frequency powered implants. It was our goal to make these stimulation methods applicable for EPR by a battery-powered nerve stimulator that would maximize the patient's freedom of movement. Additionally, the system should allow the implementation of multichannel techniques and alternating stimulation of 2 skeletal muscles as a further improvement in graciloplasty. Generally, the developed implantable nerve stimulator can be used for simultaneous and alternating activation of 2 skeletal muscles. Stimulation of the motor nerve is achieved by either single channel or multichannel methods. Carousel stimulation and sequential stimulation can be used for graciloplasty as well as for EPR. For EPR we calculated an operating time of the implant battery of 4.1 years based on the clinically used stimulation parameters with carousel stimulation. The multichannel pulse generator is hermetically sealed in a titanium case sized 65 x 17 mm (diameter x height) and weighs 88 g.

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Section: Resultsmentioning

confidence: 99%

“…Nerve pacing is effected by ring shaped stainless steel electrodes. These epineurial electrodes are used clinically in the Vienna phrenic pacemaker ( 5).…”

Section: Methodsmentioning

confidence: 99%

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confidence: 99%

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Battery‐Powered Implantable Nerve Stimulator for Chronic Activation of Two Skeletal Muscles Using Multichannel Techniques

et al. 1999

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“…The electrodes are produced in our laboratory, based on the design of the epineurial electrodes which are used clinically for the "Vienna Phrenic Pacemaker" [8]. The leads for both types are manufactured of stainless-steel stranded wire (Ethicon 612P, Ethicon Co., Norderstedt, Germany), coiled and embedded in silicone rubber (Silastic, Dow Corning, S.A., France).…”

Section: Electrodesmentioning

confidence: 99%

“…Implants that are powered transcutaneously such äs electrical pacing Systems for respiration use an external high-frequency transmitter for supplying energy and for control of the pulse generator [4,8,9]. The Stimulation data are stored in the external programmer, which also sets the timing of the nerve excitation.…”

Section: Introductionmentioning

confidence: 99%

Battery-powered Miniature Implant for Electrical Nerve Stimulation - Batteriebetriebenes Miniaturimplantat für die nervale Elektrostimulation

Lanmüller¹,

Sauermann²,

Unger³

et al. 1999

Biomedizinische Technik/Biomedical Engineering

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The range of application of implantable stimulators in functional electrical stimulation (FES) for therapeutic purposes and for the restoration of lost or damaged functions has steadily grown within the last 20 years. Each time a clinically used method is improved, a new field of FES application explored or basic research conducted, animal experiments are needed to check and evaluate the findings and results. It is precisely for this use that the stimulation system described in this paper was developed. The battery-powered single-channel stimulator can be used for the excitation of motor and sensory nerves with monophasic or biphasic impulses. All parameters and functions are programmable via the bidirectional telemetry circuit. Implant programming is achieved by a laptop computer, supported by a graphical user interface, instead of by a specially designed programmer. The maximum settings of the stimulation parameters are: frequency 100 Hz, monophasic pulse duration 0.8 ms, biphasic pulse duration 1.6 ms, stimulation current 3 mA. The implant volume was reduced to 2 cm3 (length 23 mm, width 13 mm, height 7.5 mm), lowering the weight to 3.6 g. Due to this small volume the implant can be used in small animals. The power supply via battery obviates the need for transcutaneous tunneling or permanent external high-frequency senders and facilitates the keeping of the animals.

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Microtechnical Interfaces to Neurons

Meyer

1998

Topics in Current Chemistry

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Multichannel Stimulation of Phrenic Nerves by Epineural Electrodes

Cited by 10 publications

References 0 publications

Battery‐Powered Implantable Nerve Stimulator for Chronic Activation of Two Skeletal Muscles Using Multichannel Techniques

Battery‐Powered Implantable Nerve Stimulator for Chronic Activation of Two Skeletal Muscles Using Multichannel Techniques

Battery-powered Miniature Implant for Electrical Nerve Stimulation - Batteriebetriebenes Miniaturimplantat für die nervale Elektrostimulation

Microtechnical Interfaces to Neurons

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