Multi-Scale Tumor Localization Based on Priori Guidance-Based Segmentation Method for Osteosarcoma MRI Images

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Osteosarcoma is one of the most common bone tumors that occurs in adolescents. Doctors often use magnetic resonance imaging (MRI) through biosensors to diagnose and predict osteosarcoma. However, a number of osteosarcoma MRI images have the problem of the tumor shape boundary being vague, complex, or irregular, which causes doctors to encounter difficulties in diagnosis and also makes some deep learning methods lose segmentation details as well as fail to locate the region of the osteosarcoma. In this article, we propose a novel boundary-aware grid contextual attention net (BA-GCA Net) to solve the problem of insufficient accuracy in osteosarcoma MRI image segmentation. First, a novel grid contextual attention (GCA) is designed to better capture the texture details of the tumor area. Then the statistical texture learning block (STLB) and the spatial transformer block (STB) are integrated into the network to improve its ability to extract statistical texture features and locate tumor areas. Over 80,000 MRI images of osteosarcoma from the Second Xiangya Hospital are adopted as a dataset for training, testing, and ablation studies. Results show that our proposed method achieves higher segmentation accuracy than existing methods with only a slight increase in the number of parameters and computational complexity.

Section: Introductionmentioning

confidence: 99%

BA-GCA Net: Boundary-Aware Grid Contextual Attention Net in Osteosarcoma MRI Image Segmentation

Liu

Gou

et al. 2022

Self Cite

“…However, the optimal depth of such design is unknown, and their skip connections will lead to unnecessary restrictive fusion patterns [18][19][20]. Only equally scaled feature maps in the encoder and decoder subnets can be aggregated, and the processing of data in different dimensions is not precise and comprehensive [21].…”

Section: Introductionmentioning

confidence: 99%

A Residual Fusion Network for Osteosarcoma MRI Image Segmentation in Developing Countries

Zhou

Gou

et al. 2022

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Among primary bone cancers, osteosarcoma is the most common, peaking between the ages of a child’s rapid bone growth and adolescence. The diagnosis of osteosarcoma requires observing the radiological appearance of the infected bones. A common approach is MRI, but the manual diagnosis of MRI images is prone to observer bias and inaccuracy and is rather time consuming. The MRI images of osteosarcoma contain semantic messages in several different resolutions, which are often ignored by current segmentation techniques, leading to low generalizability and accuracy. In the meantime, the boundaries between osteosarcoma and bones or other tissues are sometimes too ambiguous to separate, making it a challenging job for inexperienced doctors to draw a line between them. In this paper, we propose using a multiscale residual fusion network to handle the MRI images. We placed a novel subnetwork after the encoders to exchange information between the feature maps of different resolutions, to fuse the information they contain. The outputs are then directed to both the decoders and a shape flow block, used for improving the spatial accuracy of the segmentation map. We tested over 80,000 osteosarcoma MRI images from the PET-CT center of a well-known hospital in China. Our approach can significantly improve the effectiveness of the semantic segmentation of osteosarcoma images. Our method has higher F1, DSC, and IOU compared with other models while maintaining the number of parameters and FLOPS.

“…A large amount of data can only be diagnosed by doctors' manual identification [ 11 , 12 ], which burdens doctors. Long-term high-intensity work can also fatigue doctors and reduce the speed and accuracy of discrimination [ 13 ]. Worst of all, the location, structure, shape, and density of different osteosarcomas are not identical [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net

Liu

Zhu

et al. 2022

Self Cite

One of the most prevalent malignant bone tumors is osteosarcoma. The diagnosis and treatment cycle are long and the prognosis is poor. It takes a lot of time to manually identify osteosarcoma from osteosarcoma magnetic resonance imaging (MRI). Medical image processing technology has greatly alleviated the problems faced by medical diagnoses. However, MRI images of osteosarcoma are characterized by high noise and blurred edges. The complex features increase the difficulty of lesion area identification. Therefore, this study proposes an osteosarcoma MRI image segmentation method (OSTransnet) based on Transformer and U-net. This technique primarily addresses the issues of fuzzy tumor edge segmentation and overfitting brought on by data noise. First, we optimize the dataset by changing the precise spatial distribution of noise and the data-increment image rotation process. The tumor is then segmented based on the model of U-Net and Transformer with edge improvement. It compensates for the limitations of U-semantic Net by using channel-based transformers. Finally, we also add an edge enhancement module (BAB) and a combined loss function to improve the performance of edge segmentation. The method’s accuracy and stability are demonstrated by the detection and training results based on more than 4,000 MRI images of osteosarcoma, which also demonstrate how well the method works as an adjunct to clinical diagnosis and treatment.