Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. It has a high degree of malignancy and a poor prognosis in developing countries. The doctor manually explained that magnetic resonance imaging (MRI) suffers from subjectivity and fatigue limitations. In addition, the structure, shape, and position of osteosarcoma are complicated, and there is a lot of noise in MRI images. Directly inputting the original data set into the automatic segmentation system will bring noise and cause the model’s segmentation accuracy to decrease. Therefore, this paper proposes an osteosarcoma MRI image segmentation system based on a deep convolution neural network, which solves the overfitting problem caused by noisy data and improves the generalization performance of the model. Firstly, we use Mean Teacher to optimize the data set. The noise data is put into the second round of training of the model to improve the robustness of the model. Then, we segment the image using a deep separable U-shaped network (SepUNet) and conditional random field (CRF). SepUnet can segment lesion regions of different sizes at multiple scales; CRF further optimizes the boundary. Finally, this article calculates the area of the tumor area, which provides a more intuitive reference for assisting doctors in diagnosis. More than 80000 MRI images of osteosarcoma from three hospitals in China were tested. The results show that the proposed method guarantees the balance of speed, accuracy, and cost under the premise of improving accuracy.
In many regions of the world, early diagnosis of non-small cell lung cancer (NSCLC) is a major challenge due to the large population and lack of medical resources, which is difficult toeffectively address via limited physician manpower alone. Therefore, we developed a convolutional neural network (CNN)-based assisted diagnosis and decision-making intelligent medical system with sensors. This system analyzes NSCLC patients’ medical records using sensors to assist staging a diagnosis and provides recommended treatment plans to physicians. To address the problem of unbalanced case samples across pathological stages, we used transfer learning and dynamic sampling techniques to reconstruct and iteratively train the model to improve the accuracy of the prediction system. In this paper, all data for training and testing the system were obtained from the medical records of 2,789,675 patients with NSCLC, which were recorded in three hospitals in China over a five-year period. When the number of case samples reached 8000, the system achieved an accuracy rate of 0.84, which is already close to that of the doctors (accuracy: 0.86). The experimental results proved that the system can quickly and accurately analyze patient data and provide decision information support for physicians.
Osteosarcoma is a primary malignant tumor. It is difficult to cure and expensive to treat. Generally, diagnosis is made by analyzing MRI images of patients. In the process of clinical diagnosis, the mainstream method is the still time-consuming and laborious manual screening. Modern computer image segmentation technology can realize the automatic processing of the original image of osteosarcoma and assist doctors in diagnosis. However, to achieve a better effect of segmentation, the complexity of the model is relatively high, and the hardware conditions in developing countries are limited, so it is difficult to use it directly. Based on this situation, we propose an osteosarcoma aided segmentation method based on a guided aggregated bilateral network (OSGABN), which improves the segmentation accuracy of the model and greatly reduces the parameter scale, effectively alleviating the above problems. The fast bilateral segmentation network (FaBiNet) is used to segment images. It is a high-precision model with a detail branch that captures low-level information and a lightweight semantic branch that captures high-level semantic context. We used more than 80,000 osteosarcoma MRI images from three hospitals in China for detection, and the results showed that our model can achieve an accuracy of around 0.95 and a params of 2.33 M.
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