Multi-modal hard x-ray imaging with a laboratory source using selective reflection from a mirror

Abstract

Multi-modal hard x-ray imaging sensitive to absorption, refraction, phase and scattering contrast is demonstrated using a simple setup implemented with a laboratory source. The method is based on selective reflection at the edge of a mirror, aligned to partially reflect a pencil x-ray beam after its interaction with a sample. Quantitative scattering contrast from a test sample is experimentally demonstrated using this method. Multi-modal imaging of a house fly (Musca domestica) is shown as proof of principle of the technique for biological samples. References and links1. A. Bravin, P. Coan, and P. Suortti, "X-ray phase-contrast imaging: from pre-clinical applications towards clinics," Phys. Med. Biol. 58(1), R1-R35 (2013). 2. U. Bonse and M. Hart, "An X-ray interferometer," Appl. Phys. Lett. 6(8), 155-156 (1965). 3. S. W. Wilkins, T. E. Gureyev, D. Gao, A. Pogany, and A. W. Stevenson, "Phase-contrast imaging using polychromatic hard X-rays," Nature 384(6607), 335-338 (1996). 4. A. Momose, "Demonstration of phase-contrast X-ray computed tomography using an X-ray interferometer,"Nucl. Instrum. Vallazza, and E. Castelli, "An innovative digital imaging set-up allowing a low-dose approach to phase contrast applications in the medical field," Med.

Absorption, refraction and scattering retrieval with an edge-illumination-based imaging setup

“…Applications of XPCI are extremely vast, ranging from biological and medical to security inspection and materials science. Several approaches exist for obtaining phase-contrast images in the X-ray regime, using large-scale synchrotron facilities and more compact X-ray-tube-based equipment [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. The imaging methods, their developments and applications can also be found in recent reviews on the subject [18][19][20][21].…”