Current designs of artificial metamaterials with giant Poisson's ratios proposed microlattices that secrete the transverse displacement nonlinearly varies with the longitudinal displacement, and thePoisson's ratio depends on the applied strain (i.e., tailorable Poisson's ratio). Whereas metamaterials with tailorable Poisson's ratios would find many important applications, the design of a metamaterial with a giant Poisson's ratio that is constant over all the material deformation range has been a major challenge. Here, we develop a new class of bimaterial-3D-metamaterials with giant and strainindependent Poisson's ratios (i.e., Poisson's ratio is constant over the entire deformation range). The unit cell is 3D assembled of hinged-struts. Specially designed spherical hinges were utilized to give constant Poisson's ratios. This new class of metamaterials has been demonstrated by means of experimental and numerical mechanics. 15 material samples were 3D printed by Stereolithography (SLA) and tested. We revealed a robust anisotropy dependence of the Poisson's ratio. A giant negative Poisson's ratio of −16 was obtained utilizing a highly anisotropic unit cell of dissimilar materials and stiffnesses. Materials with giant and strain-independent Poisson's ratios provide a new class of artificial metamaterials, which would be used to optimize the performance of many existing devices, e.g., strain amplifiers and gauges.Artificial metamaterials are multiscale materials with exceptional macroscopic behaviors arising from the design of their microstructures beyond those of conventional materials found in nature 1,2 . The microstructure of a metamaterial can be tailored and optimized to promote the activation of nontraditional microscopic phenomena 2,3 . When these phenomena are activated, a metamaterial exhibits extraordinary behaviors beyond those observed in conventional materials. For example, membrane-type acoustic metamaterials with weak elastic moduli can give low-frequency oscillation patterns, which would produce an equivalent negative mass density of sound attenuation in specific frequency ranges 4-6 . In addition, metamaterials of cubic symmetric 3D-unit cells with special topologies that promote microstructural buckling can give auxetic behaviors; i.e., an auxetic metamaterial is a material with a negative Poisson's ratio 7 . Furthermore, metamaterials with crosslinked-3D unit cells can be fabricated to give an equivalent negative static compressibility 8 . By tailoring the mechanism of interaction between the inclusions and the matrix, composite metamaterials with equivalent negative mass densities, moduli, and/or Poisson's ratios can be obtained 2,9-12 . A unit cell of hexagonal sub-units has been proposed to give a mechanical metamaterial with negative stiffness and negative Poisson's ratio 13 . Other approaches that have been used for making metamaterials with negative Poisson's ratios depended on hierarchical 14 , chiral 15,16 , kirigami 17,18 , and lattice 19,20 unit cells. Recently, mechanical metamaterials ...