Multi-margin optimization with daily selection (mmods) for image-guided radiotherapy

Ruchala, K; Olivera, G.; Kapatoes, Jeff; Jeraj, Robert; Reckwerdt, Paul; Lü, Wei

doi:10.1016/s0360-3016(02)03608-8

Cited by 5 publications

(2 citation statements)

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“…Many studies have suggested the use of "a ROI" to perform rigid-body image registration using mutual information as a cost function. 6,11,12 For clarity purposes, we will refer to registrations using mutual information as a cost function as "MI registration." Since MI registration considers only the image portion within the ROI and all pixels within the ROI with equal importance, there are a few problems.…”

Section: Ib Rigid-body Registration With Regions Of Interestmentioning

confidence: 99%

Spatially weighted mutual information image registration for image guided radiation therapy

Park¹,

Rhee²,

Monroe³

et al. 2010

Medical Physics

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Section: Ib Rigid-body Registration With Regions Of Interestmentioning

confidence: 99%

Spatially weighted mutual information image registration for image guided radiation therapy

Park¹,

Rhee²,

Monroe³

et al. 2010

Medical Physics

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“…We hypothesized that a 3-mm isotropic target margin adequately covers the prostate and seminal vesicles (SVs) targets during administration of an IMRT fraction, assuming that daily image-guided setup is perfectly performed before each fraction. The choice of a 3-mm target margin to account for intrafractional anatomic variation is based on the experience of previous investigators (28,29) and results from a recent analysis of anatomic variations. (30) In this study, we acquired two CT scans, one immediately before and the other immediately after an IMRT fraction in 46 patients.…”

Section: Introductionmentioning

confidence: 99%

Is a 3-mm intrafractional margin sufficient for daily image-guided intensity-modulated radiation therapy of prostate cancer?

Melancon

O’Daniel

Zhang

et al. 2007

Radiotherapy and Oncology

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Purpose-To determine whether a 3-mm isotropic target margin adequately covers the prostate and seminal vesicles (SVs) during administration of an intensity-modulated radiation therapy (IMRT) treatment fraction, assuming that daily image-guided setup is performed just before each fraction.Methods and Materials-In-room computed tomographic (CT) scans were acquired immediately before and after a daily treatment fraction in 46 patients with prostate cancer. An eight-field IMRT plan was designed using the pre-fraction CT with a 3-mm margin and subsequently recalculated on the post-fraction CT. For convenience of comparison, dose plans were scaled to full course of treatment (75.6 Gy). Dose coverage was assessed on the post-treatment CT image set.Results-During one treatment fraction (21.4 ± 5.5 minutes), there were reductions in the volumes of the prostate and SVs receiving the prescribed dose (median reduction 0.1% and 1.0% respectively, p <0.001) and in the minimum dose to 0.1 cm 3 of their volumes (median reduction 0.5 Gy and 1.5 Gy, p <0.001). Of the 46 patients, three patients' prostates and eight patients' SVs did not maintain dose coverage above 70 Gy. Rectal filling correlated with decreased percentage-volume of SV receiving 75.6, 70, and 60 Gy (p <0.02). CONFLICTS OF INTEREST NOTIFICATIONNone of the authors have any actual or potential conflicts of interest.Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. NIH Public Access

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Adaptive Radiation Therapy (ART) Strategies Using Helical Tomotherapy

Olivera¹,

Mackie²,

Ruchala³

et al. 2006

Image-Guided IMRT

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Multi-margin optimization with daily selection (mmods) for image-guided radiotherapy

Cited by 5 publications

References 0 publications

Spatially weighted mutual information image registration for image guided radiation therapy

Spatially weighted mutual information image registration for image guided radiation therapy

Is a 3-mm intrafractional margin sufficient for daily image-guided intensity-modulated radiation therapy of prostate cancer?

Adaptive Radiation Therapy (ART) Strategies Using Helical Tomotherapy

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