Multi-class method for the determination of nitroimidazoles, nitrofurans, and chloramphenicol in chicken muscle and egg by dispersive-solid phase extraction and ultra-high performance liquid chromatography-tandem mass spectrometry

Zhang, Zhiwen; Wu, Yongjiang; Li, Xiaowei; Wang, Yingyu; Li, Hui; Fu, Qin; Shan, Yawen; Liu, Tianhe; Xia, Xi

doi:10.1016/j.foodchem.2016.08.097

Cited by 53 publications

(22 citation statements)

References 36 publications

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“…Due to their toxic effects, the use of CAP has been prohibited in veterinary medicine in China, Japan, Canada, United States, and EU (Barreto, Ribeiro, Barcellos Hoff, & Dalla Costa, 2016; Imran et al., 2017, 2018; Kikuchi et al., 2017). The EC has set the MRPL for this antibiotic at 0.3 µg kg –1 in food‐producing animals (Barreto et al., 2016; Kikuchi et al., 2017; Zhang et al., 2017). However, for other APs, such as florfenicol (FFC) and thiamphenicol, the MRL are 100 µg kg –1 and 50 µg kg –1 in poultry chicken, respectively (Wang et al., 2019).…”

Section: Analytical Methodologies For the Analysis Of The Principal Amentioning

confidence: 99%

Determination of antibiotics in meat samples using analytical methodologies: A review

Moga

Vergara-Barberán

Lerma‐García

et al. 2021

Comp Rev Food Sci Food Safe

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Antibiotics are widely used to prevent or treat some diseases in human and veterinary medicine and also as animal growth promoters. The presence of these compounds in foods derived from food‐producing animals can be a risk for human health. Consequently, regulatory agencies have set maximum residue limits for antibiotics in food samples. Therefore, the development of novel methodologies for its determination in food samples is required. Specifically, the analysis and quantification of these substances in meat tissues is a challenge for the analytical chemistry research community. This is due to the complexity of the matrix and the low detection limits required by the regulatory agencies. In this sense, a comprehensive review on the development of new sample preparation treatments involving extraction, cleanup, and enrichment steps of antibiotics in meat samples in combination with sensitive and sophisticated determination techniques that have been carry out in the last years is necessary. Therefore, the aim of this work is to summarize the published methodologies for the determination of antibiotics from 2016 until the beginning of the second semester of 2020. The first part of this review includes an introduction about antibiotic families, followed by sample preparation and determination techniques applied to the different families. Finally, a detailed discussion of the current trends and the future possible perspectives in this field are also included.

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Section: Analytical Methodologies For the Analysis Of The Principal Amentioning

confidence: 99%

Determination of antibiotics in meat samples using analytical methodologies: A review

Moga

Vergara-Barberán

Lerma‐García

et al. 2021

Comp Rev Food Sci Food Safe

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“…However, this process could be affected by interferers present in the analytical matrix, minimizing in some cases the percent retention and subsequent percent recovery. For these reasons, in some cases, additional clean-up steps are necessary to diminish the amount of interferers before analysis of benzimidazole anthelmintic (BAs) [ 33 ], bisphenol A [ 52 ], nitroimidazoles [ 21 ], nitrofurans [ 86 ], chloramphenicol [ 86 ], QNs [ 23 , 29 , 57 ], TCs [ 43 ], SAs [ 22 ], and β -lactams [ 45 ]. In the cited works, limits of detection were obtained in the order of 0.03–123 μ g kg −1 and 0.7–35.5 ng mL −1 in function of the sample, with % recovery of 58% in the analysis of β -lactams until 116% for nitroimidazoles, nitrofurans, and chloramphenicol.…”

Section: Application Of Dispersive Solid Phase Extraction: Analysimentioning

confidence: 99%

Dispersive Solid Phase Extraction for the Analysis of Veterinary Drugs Applied to Food Samples: A Review

Islas

Ibarra

Hernández³

et al. 2017

International Journal of Analytical Chemistry

113

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To achieve analytical success, it is necessary to develop thorough clean-up procedures to extract analytes from the matrix. Dispersive solid phase extraction (DSPE) has been used as a pretreatment technique for the analysis of several compounds. This technique is based on the dispersion of a solid sorbent in liquid samples in the extraction isolation and clean-up of different analytes from complex matrices. DSPE has found a wide range of applications in several fields, and it is considered to be a selective, robust, and versatile technique. The applications of dispersive techniques in the analysis of veterinary drugs in different matrices involve magnetic sorbents, molecularly imprinted polymers, carbon-based nanomaterials, and the Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) method. Techniques based on DSPE permit minimization of additional steps such as precipitation, centrifugation, and filtration, which decreases the manipulation of the sample. In this review, we describe the main procedures used for synthesis, characterization, and application of this pretreatment technique and how it has been applied to food analysis.

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“…In addition, soil and water quality control is very important. Determination of CAP in a complex matrix requires extraction and separation, which are time‐consuming . Thus, it is highly desirable to develop a rapid and sensitive tool for on‐site detection of CAP.…”

Section: Introductionmentioning

confidence: 99%

Fluorescence studies of the interaction between chloramphenicol and nitrogen‐doped graphene quantum dots and determination of chloramphenicol in chicken feed

Tsai

Hsieh

et al. 2019

J Chinese Chemical Soc

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Chloramphenicol (CAP) is a veterinary antibiotic that has been banned due to its severe side effects in humans. Through the application of manure, veterinary antibiotics can enter the soil, where they can be taken up by crops and vegetables and pose a potential health hazard to humans. Thus, it is highly desirable to develop a rapid and sensitive tool for on-site detection of CAP to ensure food safety and to control the abuse of antibiotics. To this end, nitrogen-doped graphene quantum dots (N-GQDs) were successfully prepared via microwave-assisted synthesis using citric acid and urea as carbon and nitrogen sources, respectively. Analytical results suggested that the interaction between N-GQDs and CAP could occurs via π-π stacking, which quenched N-GQD fluorescence. CAP spiked into chicken feed could be rapidly extracted with ethanol and quantified based on N-GQD fluorescence quenching without further separation. This method showed good recovery (97-102.6%), a low detection limit (1.8 ppm), and was not affected by interference from florfenicol, and thiamphenicol, legal substitute antibiotics. This method has excellent potential for determination of CAP in livestock feed and soil. K E Y W O R D Schloramphenicol, fluorescence quenching, graphene quantum dots, nitrogen doping

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Multi-class method for the determination of nitroimidazoles, nitrofurans, and chloramphenicol in chicken muscle and egg by dispersive-solid phase extraction and ultra-high performance liquid chromatography-tandem mass spectrometry

Cited by 53 publications

References 36 publications

Determination of antibiotics in meat samples using analytical methodologies: A review

Determination of antibiotics in meat samples using analytical methodologies: A review

Dispersive Solid Phase Extraction for the Analysis of Veterinary Drugs Applied to Food Samples: A Review

Fluorescence studies of the interaction between chloramphenicol and nitrogen‐doped graphene quantum dots and determination of chloramphenicol in chicken feed

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