The 1.4-1.8 μm eye-safe lasers have been widely used in the fields of laser medicine and laser detection and ranging. The diamond Raman lasers are capable of delivering excellent characteristics, such as good beam quality concomitantly with high output power. The intra-cavity diamond Raman lasers have the advantages of compactness and low Raman thresholds compared to the external-cavity Raman lasers. However, to date, the intra-cavity diamond cascaded Raman lasers in the spectral region of the eye-safe laser have an output power of only a few hundred milliwatts. A 1485 nm Nd:YVO 4 /diamond intra-cavity cascaded Raman laser is reported in this paper. The mode matching and stability of the cavity were optimally designed by a V-shaped folded cavity, which yielded an average output power of up to 2.2 W at a pulse repetition frequency of 50 kHz with a diode to second-Stokes conversion efficiency of 8.1%. Meanwhile, the pulse width of the second-Stokes laser was drastically reduced from 60 ns of the fundamental laser to 1.1 ns, which resulted in a high peak power of 40 kW. The device also exhibited single longitudinal mode with a narrow spectral width of < 0.02 nm.