Mucosal malignant melanoma of the nasal cavity

Bothale, Kalpana; Maimoon, Sabiha; Patrikar, Anjali; Mahore, Sadhana

doi:10.4103/0019-509x.48600

Cited by 7 publications

(3 citation statements)

References 5 publications

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“…Nasoendoscopy usually reveals the large mass obliterating nasal cavity. Some cases described the mass as reddish pink with black pigmentation at base, and firm in consistency with irregular surface [8].…”

Section: Discussionmentioning

confidence: 99%

Sino-Nasal Malignant Melanoma: A Case Report

Yee¹,

Gill²,

Kumarasamy³

et al. 2023

IJOHNS

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Melanoma is a malignant tumor and is commonly found second least in the head and neck region, with approximately 10% -25% of melanomas followed by ear (8% -11%). We reported a case of sino-nasal malignant melanoma in a 46-year-old Asian lady who presented with epistaxis and dysphagia. By nasoendoscopy and CT scan imaging, the diagnosis of sino-nasal malignant melanoma was later confirmed by histopathology examination along with immunohistochemistry by using Melan A and S100. Malignant melanoma in the head and neck is rare and has a poor prognosis. There has been an increase in the incidence of 5% per year and mortality at 2% per year. This dictates malignant melanoma has rapidly increased compared to any other cancer except lung cancer in women and has contributed to the third highest number of deaths among all cancers. The mortality rate has also increased, and that is attributed to the negligence of symptoms during the initial period. This usually leads to patients seeking consultation during the advanced stage of the disease. In conclusion, this paper is to report that malignant melanoma may be one of the differentials of sino-nasal masses, and it may mimic nasopharyngeal carcinoma in its presentation.

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Section: Discussionmentioning

confidence: 99%

Sino-Nasal Malignant Melanoma: A Case Report

Yee¹,

Gill²,

Kumarasamy³

et al. 2023

IJOHNS

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“…They are more common in men as compared to women. 8 Mucosal melanomas are more aggressive than cutaneous melanomas and have a poorer outcome. Primary malignant melanoma of nasal cavity is one rare disease which requires complete evaluation because of its aggressive nature and high chances of local and distant metastases and poor detection rates.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Primary Malignant Melanoma of Nasal Cavity

D¹,

Paventhan²,

Puneeth³

et al. 2015

jebmh

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“…Most of the melanomas arise in the sun exposed areas, i.e., head and neck area and on lower extremities. Twenty to twenty-five percent of melanoma cases occur in head and neck region out of which approximately 6-8% originates in mucous membrane of upper aerodigestive tract [2]. The most common site for mucosal melanomas in the head and neck region is oral cavity followed by sinonasal region and lastly pharynx.…”

Section: Discussionmentioning

confidence: 99%

Malignant mucosal melanoma of the nasal cavity: A case report

Gupta¹,

Goyal²,

Rana³

et al. 2014

IJCRI

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International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations.IJCRI publishes Review Articles, Case Series, Case Reports, Case in Images, Clinical Images and Letters to Editor. Website: www.ijcasereportsandimages.comMalignant mucosal melanoma of the nasal cavity:A case report Devika Gupta, Niti Goyal, Vandana Rana, Rajat Jagani, Davendra Swarup ABSTRACT Introduction: Mucosal melanoma of the nasal cavity is a rare tumor. It is seen more commonly in the elderly and is known to have a male preponderance. Patients often present with nonspecific symptoms of nasal obstruction or epistaxis. These tumors carry a poor prognosis because of higher rates of locoregional recurrence and distant metastasis. Case Report: We report a 54-year-old male who presented with submandibular swelling and history of episodes of occasional epistaxis. Microscopic examination of the excision biopsy of the submandibular lymph node supported with immunohistochemistry (IHC) was suggestive of metastatic deposit of malignant melanoma. Clinical examination and radiological imaging for the primary tumor lead to detection of a mass in the right nasal cavity. Histopathology of wide local excision of nasal mass confirmed the diagnosis. Conclusion: Malignant melanomas can mimic a large number of malignant diseases and early diagnosis by astute pathologist can help achieve attain long time remission.

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Mucosal malignant melanoma of the nasal cavity

Cited by 7 publications

References 5 publications

Sino-Nasal Malignant Melanoma: A Case Report

Sino-Nasal Malignant Melanoma: A Case Report

A Rare Case of Primary Malignant Melanoma of Nasal Cavity

Malignant mucosal melanoma of the nasal cavity: A case report

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