Mucosa-associated lymphoid tissue lymphoma on right lower eyelid previously diagnosed as lymphoid hyperplasia

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma is an uncommon form of non-Hodgkin lymphoma involving the mucosa-associated lymphoid tissue. Most commonly affected organ is the stomach. But, it could affect almost every organ in the whole body. If they have suspicious lesion, excision biopsy could be made. For staging, blood test including blood smear, abdomen and chest tomography or scan will be checked. Also, bone marrow test can be done if it is needed. The patient had visited the clinic for palpable mass on right lower eyelid. With excisional biopsy, it was diagnosed as lymphoid hyperplasia on pathologic test. But 2 years later, the patient came with recurrent symptom for our department with worry. At that time, we recommended excisional soft tissue biopsy under general anesthesia. Unfortunately, it was revealed MALT lymphoma on pathologic finding. It turned out to be stage 3 in Ann Arbor staging system without B symptoms. Hematologic consultation was made and she was treated with adjuvant chemotherapy for eight cycles to complete remission. We report a case of MALT lymphoma on subcutaneous tissue at right lower eyelid previously diagnosed as lymphoid hyperplasia.

Primary non-Hodgkin lymphoma of the parotid gland: a case report

“…Although NHL is the second most common neoplasm in the head and neck region, primary parotid NHL accounts for only 1% to 4% of all parotid tumors [ 4 ]. The three most common subtypes of primary parotid NHL are extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue, follicular lymphoma, and diffuse large B-cell lymphoma, all of which originate from B lymphocytes [ 5 ]. Salivary gland lymphomas are frequently associated with a history of autoimmune diseases such as Sjögren syndrome [ 6 ].…”