Mucormycosis in leukemia

Rosenberg, Simon W.; Lepley, James B.

doi:10.1016/0030-4220(82)90413-3

Cited by 19 publications

(11 citation statements)

References 17 publications

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“…The majority cases of oral mucormycosis have been found in the fourth to sixth decades of life 8 9 10 11 . This is because oral mucormycosis mainly target immunocompromised patients such as those with uncontrolled diabetic, leukemia, lymphoma, and AIDS 1 2 . The same is not always true because healthy humans are also, but rarely, affected by mucormycosis; this might be due to exposure to various predisposing risk factors.…”

Section: Discussionmentioning

confidence: 99%

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Oral mucormycosis in an 18-month-old child: a rare case report with a literature review

Kalaskar

Ganvir

2016

J Korean Assoc Oral Maxillofac Surg

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Oral mucormycosis is a fungal infection observed mainly in elderly immunocompromised patients. In rare instances, the disease occurs in healthy individuals and those patients that are below preschool age. Although this condition mainly involves the maxilla, it may also manifest in any part of the oral cavity based on the source of infection. Mucormycosis of the maxilla spreads rapidly, leading to necrosis of the palatal bone and palatal perforation. Such patients are usually rehabilitated using bone grafting or free flap surgeries. However, when surgeries are delayed, palatal prosthesis is an interim treatment modality that can prevent nasal regurgitation and aspiration of food or fluids. Palatal prostheses also help with mastication, speech, and swallowing. The present case describes a rare case of oral mucormycosis in an 18-month-old male involving the maxilla that was managed by palatal prosthesis.

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Section: Discussionmentioning

confidence: 99%

“…Mucormycosis is an acute opportunistic infection usually seen in immunocompromised patients, particularly those with uncontrolled diabetes and leukemia 1 2 . Paltauf 3 in 1885 was the first to describe mucormycosis.…”

Section: Introductionmentioning

confidence: 99%

Oral mucormycosis in an 18-month-old child: a rare case report with a literature review

Kalaskar

Ganvir

2016

J Korean Assoc Oral Maxillofac Surg

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“…However, the possibility of correction is hardly applicable to oncological patients 3 , 16 , 30 – 32 . Neutrophils are the primary defence against fungal infections such as mucormycosis, and neutropenia can increase the risk of infection 33 – 35 . Absolute neutrophil counts below 500 cells/ml are strongly correlated with the development of invasive fungal disease 36 .…”

Section: Discussionmentioning

confidence: 99%

Rhinocerebral mucormycosis: experience in 14 patients

et al. 2011

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“…Except of this cerebral mucormycosis no further foci of infection were detected.Opportunistische Pilzinfektionen bei Patienten mit einer malignen Erkrankung, vor allem Leukamien und Lymphomen, stellen immer wieder ein grol3es Problem dar (3). Neben Candidiasis und Aspergillose tritt in seltenen Fallen eine Mucormykose auf (3,5,12). Die pulmonale und disseminierte Form der Mucormykose finden sich am haufigsten bei immungeschwachten Patienten, wohingegen die rhinocerebrale Form haufiger bei Diabetikern beobachtet wird (2,5,8,10,11).…”

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“…Opportunistische Pilzinfektionen bei Patienten mit einer malignen Erkrankung, vor allem Leukamien und Lymphomen, stellen immer wieder ein grol3es Problem dar (3). Neben Candidiasis und Aspergillose tritt in seltenen Fallen eine Mucormykose auf (3,5,12…”

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Isolierte Cerebrale Mucormykose bei Leukämie: Isolated Cerebral Mucormycosis in a Patient with Leukemia

Bachor

Baczako

Kern

1986

Mycoses

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Zusammenfassung: Mucormykosen stellen seltene Infektionen dar. Bei Diabetikern fmdet man vor allem die rhinocerebrale, bei immungeschwachten Patienten dagegen die pulmonale und disseminierte Form. Wir berichten iiber eine Patientin im Stadium der Vollremission einer akuten lymphatischen Leukiimie, die klinisch an einer Meningo-Encephalitis mit Himnervenbeteiligung ohne bekannte Atiologie verstarb. Bei der Obduktion zeigte sich eine Thrombosierung der Arteria vertebralis links, die durch eine Mucorinfiitration bedingt war und zu einer h i o rrhagischen Erweichung im Kleinhirn und in der Medulla oblongata f&rte. Au6er diesercerebralen Mucormykose wurden keine weiteren Infektionsherde gefunden.Summary: Mucormycosis is a rare infection. In patients with diabetes mellihs a rhinocerebral form predominates, while in the immunocompromised host mucormycosis is mostly pulmonary or disseminated. We report on a patient in remission of an acute leukemia, who died clinically of a meningo-encephalitis with involvement of crbial nerves of unknown etiology. At autopsy a thrombosis of the left arteriavertebralis caused by mucor was found with hemonhagicnecrosis of the cerebellum and the medulla oblongata. Except of this cerebral mucormycosis no further foci of infection were detected.Opportunistische Pilzinfektionen bei Patienten mit einer malignen Erkrankung, vor allem Leukamien und Lymphomen, stellen immer wieder ein grol3es Problem dar (3). Neben Candidiasis und Aspergillose tritt in seltenen Fallen eine Mucormykose auf (3,5,12). Die pulmonale und disseminierte Form der Mucormykose finden sich am haufigsten bei immungeschwachten Patienten, wohingegen die rhinocerebrale Form haufiger bei Diabetikern beobachtet wird (2,5,8,10,11). Wir berichten iiber eine Patientin mit Leukamie, bei der klinisch eine atiologisch unklare Meningo-Encephalitis bestand, die sich bei der Autopsie als isolierte cerebrale Mucormykose herausstellte.

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Mucormycosis in leukemia

Cited by 19 publications

References 17 publications

Oral mucormycosis in an 18-month-old child: a rare case report with a literature review

Oral mucormycosis in an 18-month-old child: a rare case report with a literature review

Rhinocerebral mucormycosis: experience in 14 patients

Isolierte Cerebrale Mucormykose bei Leukämie: Isolated Cerebral Mucormycosis in a Patient with Leukemia

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