Mucormicosis rinosinusal en un paciente infectado por VIH

Abstract

Rhinosinusal mucormicosis in an HIV positive patient Mucormicosis is a fungal opportunistic infection produced by various species of Mucorales, such as Rhizopus, Mucor, Cunninghamella and Absidia. It is associated with diabetes, renal failure, blood diseases, tumors and solid organ or hematological precursors transplants. It presents with diverse clinical manifestations: rhinocerebral, renal, pulmonary, cutaneous, gastrointestinal and disseminated disease. The infection is uncommon in HIV positive patients. In 2002 at the Dr. Lucio Cordova Infectious Diseases Hospital we attended our first confirmed case, a female, HIV (+) patient, C3 CDC stage, with less than 100 CD4/mm 3 and receiving antiretroviral treatment. She presented a rhinosinusal form and diagnosis was made by CT scan and confirmed with biopsy and culture. This case was treated with amphotericin B deoxycolate and debridement of all necrotic tissue. The patient completed treatment and died one half year after treatment without reactivation of infection.

Mucormicosis cutánea en un paciente inmunocomprometido

“…Bertin, el 2003 en Valdivia, informa una mucormicosis rinosinusal en un adulto diabético 28 . El 2004, Aguad y cols., comunican un caso de zigomicosis rinocerebral en una mujer con infec-ción por VIH 29 , Chávez y cols, informa una mucormicosis rinocerebral en un niño diabético 30 , Spalloni y cols y Wicki y cols describen dos casos de mucormicosis rinocerebral en pacientes pediátricos con leucemia 31,32 .…”