Mucocutaneous Lesions of Behçet's Disease

Abstract

Behçet's disease is particularly prevalent in "Silk Route" populations, but it has a global distribution. The diagnosis of the disease is based on clinical criteria as there is as yet no pathognomonic test, and mucocutaneous lesions, which figure prominently in the presentation and diagnosis, may be considered the diagnostic hallmarks. Among the internationally accepted criteria, painful oral and genital ulcers, cutaneous vasculitic lesions and reactivity of the skin to needle prick or injection (the pathergy reaction) are considered hallmarks of Behçet's disease, and often precede other manifestations. Their recognition may permit earlier diagnosis and treatment, with salutary results. This paper describes the various lesions that constitute the syndrome and focuses on those that may be considered characteristic.

Quality of life in patients with Behcet's disease and Recurrent aphthous stomatitis

“…BH deri belirtileri, uluslararası BH kriterlerine göre, ENBL, psödofolikülit, PPL veya akneiform lezyonlar olarak tanımlanmıştır 39 . PPL klinikte en sık gözlenen deri belirtisidir 40 . Hastaların %40-70'inde beklenen bir bulgudur 41 .…”

Úlcera genital aguda asociada a eritema nudoso. ¿Cuál debería ser la primera sospecha?

“…In contrast, in Europe and the USA, the rate is 0.1-7.5/100,000 (1). Genital ulcers are one of the main components of this complex condition, as they represent the second most common sign after oral aphthae, occurring in 57-93% of cases (1). Genital ulcers are characterized by clear demarcation and great depth.…”

Dilated Cardiomyopathy in Behcet′s Disease in a Young Male Patient

“…Vascular involvement includes migratory superficial thrombophlebitis, deep venous thrombosis in veins, arteritis and aneurysm formation, which may involve the aorta or its branches. The pathergy test is helpful but is not sensitive or specific for the diagnosis of BD [21,22].…”