Mucinous Nevus

Abstract

Mucinous nevus is an uncommon entity classified as either a cutaneous mucinosis or a connective tissue nevus. The condition presents as grouped papules and coalescent plaques growing in a unilateral or zosteriform manner. The key histopathological feature is a band-like deposition of mucin in the superficial dermis. A 34-year-old male presented with grouped gray-brown papules and confluent plaques exhibiting a zosteriform distribution on the right side of the lower back. The lesions had commenced in childhood. Histological examination revealed mucin deposition in the papillary dermis. Thus, we diagnosed a mucinous nevus. To date, only a few reports of such nevi have been reported in the literature. Therefore we report a rare case of mucinous nevus.

Pediatric Lichen Myxedematosus: A Diagnostic and Management Challenge

“…Other subtypes of localized LM, such as cutaneous mucinosis of infancy, acral persistent papular mucinosis, and discrete papular mucinosis do not fit clinically [ 6 ]. Mucinous nevus was considered; however, mucinous nevi typically present unilaterally in a zosteriform distribution and exhibit characteristic band-like deposition of mucin in the superficial dermis [ 7 , 8 ]. Notably, SHJCM which can also present with generalized papules and nodules, remains on the differential, however, lesions persist without evidence of resolution to date.…”

Multidermatomal Zosteriform Collagenoma

“…We found only 14 cases of zosteriform connective tissue nevus has been described in the literature previously [ Table 1 ], with Steiner being the first to describe the condition in 1944. [ 1 2 6 7 8 9 10 11 12 13 14 15 16 17 ] Out of the 14 cases described previously, only 7 cases were collagen tissue nevus.…”

A Woman with Gradually Enlarging Brownish Confluent Papules on the Left Thigh: A Quiz

“…Mucin deposits are thought to be secondary to an over-production of hyaluronic acid (positive with Alcian blue at pH 2.5, and not staining at pH 0.5) by activated fibroblasts ( 3 , 4 ). Epidermal changes are variable and may be useful to define 2 different histopathological subsets: connective tissue naevi of the proteoglycan (CTNP) type when the epidermis is normal; and epidermal-CTNP type when hyperkeratosis and acanthosis with elongation of the rete ridges is found ( 5 , 6 ). In addition, a reduction in elastic fibres and collagen can be found in the papillary dermis, as well as a scarce cellular component, which consists of CD34-positive fibroblasts ( 7 , 8 ).…”