MRSA and Inducible Clindamycin resistance in Staphylococcus aureus from Various Samples in A Tertiary Care Hospital

Krishnan, Raja Shanmuga; Harbade, Mangala Suresh; Iravane, Jyoti; Gaikwad, Anil A.

doi:10.20546/ijcmas.2019.812.003

Cited by 1 publication

(4 citation statements)

References 6 publications

(6 reference statements)

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“…53.85% isolates of MRSA were reported sensitive gentamicin during present study. More or less similar pattern of gentamicin sensitivity was observed by Al-Zaidi and Al-Sulami (2013) [15] , Ahmad et al (2015) [19] , Selvabai et al (2017) [20] , Krishnan et al (2019) [21] and Arjyal et al (2020) [22] . However Shah et al (2019) [18] reported increased sensitivity to gentamicin.…”

Section: Antibiogram Of Mrsasupporting

confidence: 72%

“…All the isolates were found sensitive to linezolid and imipenem. Likewise present study, Mahmood et al (2010) [23] , Goyal et al (2013) [24] , Li et al (2017) [27] , Sharma et al (2017) [28] , Selvabai et al (2017) [20] , Krishnan et al (2019) [21] and Arjyal et al (2020) [22] also reported 100% sesnisitivity of MRSA towards linezolid whereas 3.8% resistance was observed by Sonth et al (2015) [26] . Variable degree of resistance to imipenem was reported by Al-Zaidi and Al-Sulami (2013) [15] and Samra and Gadba (1993) [35] .…”

Section: Antibiogram Of Mrsasupporting

confidence: 63%

“…In line with present observation Selvabai et al (2017) [20] , Sharma et al (2017) [28] , Li et al (2017) [27] , Ahmad et al (2015) [19] , Al-Zaidi and Al-Sulami (2013) [15] and Kumar et al, (2011) [33] reported fairly similar rate of sesnistivity towards clindamycin. Whereas higher rate of resistance towards clindamycin was reported by Krishnan et al (2019) [21] , Sohail and Latif (2018) [34] and Goyal et al (2013) [24] . Clindamycin, a lincosamide drug could be used to treat MRSA infection because of its good efficacy and pharmacokinetic properties.…”

Section: Antibiogram Of Mrsamentioning

confidence: 79%

“…Existance of vancomycin resistant MRSA during present study was well supported by Shah et al (2019) [18] , Nasution et al (2018) [17] and Al-Zaidi and Al-Sulami (2013) [15] . In contrast, Mahmood et al (2010) [23] , Selvabai et al (2017) [20] , Sonth et al (2015) [26] , Li et al (2017) [27] , Sharma et al (2017) [28] and Krishnan et al (2019) [21] reported 100% sensitivity of MRSA to vancomycin. Vancomycin, a glycopeptide antibiotic usually remains a drug of choice for treatment of MRSA infections.…”

Section: Antibiogram Of Mrsamentioning

confidence: 99%

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Antibiogram of methicillin resistant Staphylococcus aureus (MRSA) of animal origin from Chhattisgarh

Sannat¹,

Hirpurkar²,

Hazari³

et al. 2021

Pharma Innovation

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Present investigation was made to study antibiogram profile of Methicillin Resistant Staphylococcus aureus (MRSA) of animal origin. MRSA isolates were obtained from bovine mastitis and wound infection of animals using cultural isolation and were confirmed by S. aureus specific thermonuclease (nuc) and MRSA specific mecA gene in PCR assay. A total of 13 MRSA isolates were obtained and subjected to antibiotic sensitivity test using 10 numbers of selected antibiotics by disc diffusion test. MRSA isolates exhibited variable degree of sensitivity towards various antibiotics. MRSA isolates were detected 100% senisitive to linezolid and imipenem followed by clindamycin (92.31%), tetracycline (76.92%), vancomycin and gentamycin (53.85%). Isolates showed higher rate of resistance towards amoxicillin (84.62%) and penicillin (76.92%). All the isolates were found resistant to cefoxitin and methicillin. It can be concluded from present study that isolates harbouring mecA/ MRSA gene have tendency to exhibit resistant towards multidrug and treatment option can be explored by studying antibiogram of MRSA of particular region.

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Section: Antibiogram Of Mrsasupporting

confidence: 72%