MRI of intracranial chordomas. Extent of tumour and contrast enhancement: criteria for differential diagnosis

Doucet, V.; Peretti-Viton, P.; Figarella‐Branger, Dominique; Manera, L.; Salamon, G

doi:10.1007/s002340050469

Cited by 73 publications

(34 citation statements)

References 18 publications

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“…46,53,65 Gadolinium-enhanced MR imaging will more clearly define the extent of the disease. 28,53,65 On T 1 -weighted MR imaging, chordomas generally demonstrate a low to moderate signal intensity. 65 In some cases, scattered small areas of increased signal intensity on T 1 -weighted images can be seen.…”

mentioning

confidence: 99%

Skull base chordomas: overview of disease, management options, and outcome

Lanzino¹,

As²,

Mb³

et al. 2001

FOC

101

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Cranial base chordomas are locally invasive tumors that, from a midline, clival location, extend in different directions and display various patterns of skull base invasion. Although histologically benign, their invasive nature makes true “oncological” resection virtually impossible to achieve in most cases, despite modern skull base surgical techniques. Moreover, because of the tumor's location and proximity to critical neural and vascular structures, surgery-related morbidity can be significant when an aggressive resection is undertaken. Cytoreductive surgery assumes a critical role in the management of these lesions. The choice of surgical approach and the extent of resection are dependent on several factors: location and extension of the tumor, the surgeon's philosophy and familiarity with a specific approach, and the patient's preexisting clinical status. Proton-beam radiotherapy seems to be effective as an adjunct to surgery in achieving local tumor control. The timing of radiation therapy, however, remains controversial. Gamma knife surgery has been proposed as an adjunctive therapy, but the limited experience and short follow-up periods do not permit formulation of meaningful conclusions at this time. Recurrences are common, although in a subset of patients prolonged disease-free survival is demonstrated.

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mentioning

confidence: 99%

Skull base chordomas: overview of disease, management options, and outcome

Lanzino¹,

As²,

Mb³

et al. 2001

FOC

101

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“…The enhancement pattern of the tumor sometimes has a "honeycomb" appearance created by intratumoral areas of low signal intensity. 25 This pattern of contrast enhancement can reflect the pathologic features of such tumors, which are organized in lobules with mucinous and gelatinous contents.…”

Section: Discussionmentioning

confidence: 97%

Primary Chordoma in the Nasal Cavity and Nasopharynx: CT and MR Imaging Findings

Zhang¹,

Yang²,

Wang³

et al. 2009

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE:Primary chordoma in the nasal cavity and nasopharynx is an extremely rare tumor in the extraosseous axial skeleton. Unlike intracranial chordomas, lesions in these sites primarily present as a soft tissue mass without involvement of the skull base bone (clivus), so the preoperative diagnosis of the tumor is possibly difficult. Here, we reviewed the imaging features of 5 cases of chordomas in the nasal cavity and nasopharynx that resulted in successful diagnosis and differential diagnosis of this rare tumor.

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“…The differential diagnosis list is significantly different for extraosseous chordoma from the standard classic chordoma; due to its location. The differential for this variant lesion includes nasopharyngeal carcinoma and non-Hodgkin lymphoma [11].…”

Section: Discussionmentioning

confidence: 99%

Chordoma Arising from Cranial Base Extending to Oropharynx: An Unusual Presentation

Vasudevan

Manjunath

Devaraju

et al. 2012

J. Maxillofac. Oral Surg.

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Chordoma is a relatively rare tumor of the skull base thought to originate from embryonic remnants of the notochord. Chordomas arising from the skull base/clivus are typically locally aggressive with lytic bone destruction. When chordomas occur in an extraosseous location, they may mimic other lesions of the nasopharynx and oropharynx. We present a case of primarily extraosseous chordoma involving the oropharynx in an effort to improve the preoperative diagnosis of this rare tumor among the dental fraternity. In addition, we review regional notochordal embryology to explain this variant tumor location.

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MRI of intracranial chordomas. Extent of tumour and contrast enhancement: criteria for differential diagnosis

Cited by 73 publications

References 18 publications

Skull base chordomas: overview of disease, management options, and outcome

Skull base chordomas: overview of disease, management options, and outcome

Primary Chordoma in the Nasal Cavity and Nasopharynx: CT and MR Imaging Findings

Chordoma Arising from Cranial Base Extending to Oropharynx: An Unusual Presentation

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