1993
DOI: 10.1007/bf00588505
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MRI in craniofacial fibrous dysplasia

Abstract: Five patients with biopsy-proven craniofacial fibrous dysplasia underwent MRI with T1- and T2-weighted sequences and a gadolinium-enhanced T1-weighted spin-echo sequence. Low to intermediate signal intensity was usually seen in the largest part of the lesion on both spin-echo sequences, but smaller regions of hyperintensity on T1- and T2-weighted images and intermediate signal intensity throughout a lesion on T1-weighted images were also seen. All lesions enhanced but only two became iso- or hyperintense compa… Show more

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Cited by 84 publications
(29 citation statements)
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“…12 Magnetic resonance imaging offers excellent definition of soft-tissue and ocular involvement and allows assessment of adjacent neurovascular structures. 5,19 Of particular usefulness, MR imaging demonstrates cystic change (or mucoceles) as evident by very high signal from the cystic component seen on T 2 -weighted images and very low signal from bone sclerosis observed on T 2 -weighted images. 12 Enhancement of pathological tissue is commonly observed on MR imaging but is more difficult to discern on CT scanning.…”
Section: Radiological Characteristicsmentioning
confidence: 99%
“…12 Magnetic resonance imaging offers excellent definition of soft-tissue and ocular involvement and allows assessment of adjacent neurovascular structures. 5,19 Of particular usefulness, MR imaging demonstrates cystic change (or mucoceles) as evident by very high signal from the cystic component seen on T 2 -weighted images and very low signal from bone sclerosis observed on T 2 -weighted images. 12 Enhancement of pathological tissue is commonly observed on MR imaging but is more difficult to discern on CT scanning.…”
Section: Radiological Characteristicsmentioning
confidence: 99%
“…1,4,7,13,20) MR imaging can be useful for assessing the cellular components that can indicate malignancy. 2,10,12) Sudden, rapid disappearance of bone structures and cortical destruction after pathologic fracture suggest malignant change in fibrous dysplasia. Furthermore, [ 11 C]Met PET may reveal increasing accumulation in cases of malignant transformation of fibrous dysplasia.…”
Section: Discussionmentioning
confidence: 99%
“…Recently, magnetic resonance (MR) imaging 2,10,12) as well as radiography and computed tomography (CT) 6) have been used to identify fibrous dysplasia, which must be differentiated from other types of tumors. Bone scintigraphy with technetium-99m-hydroxymethylene diphosphonate ( 99m Tc-HMDP) has revealed increased bone mineral turnover in fibrous dysplasia.…”
Section: Introductionmentioning
confidence: 99%
“…On postgadolinium MR images, affected bones show variable enhancement, reflecting vascularity of the fibrocellular tissue. MRI offers greater specificity in neurovascular and ocular involvement and in detection of other soft tissue lesions (9).…”
Section: Ground-glass Pattern Fibrous Dysplasia Of Frontal Sinusmentioning
confidence: 99%