MRI in coronary artery disease

Barkhausen, Jörg; Hunold, Peter; Waltering, K. U.

doi:10.1007/s00330-004-2456-4

Cited by 17 publications

(14 citation statements)

References 49 publications

(43 reference statements)

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“…BB techniques are not limited to providing data on LV mass in cardiac MR; advantages have also been shown for the assessment of the coronary arteries (MRCA) [16]. Bright blood techniques have several limitations in MR angiography (MRA), including difficulty identifying luminal stenosis, as turbulent blood flow can appear as artifactual darkening.…”

Section: Discussionmentioning

confidence: 99%

The reproducibility of left ventricular volume and mass measurements: a comparison between dual-inversion-recovery black-blood sequence and SSFP

et al. 2005

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The aim of this study was to compare a dual-inversion-recovery black-blood (BB) magnetic resonance imaging (MRI) sequence with steady-state free precession (SSFP) for the assessment of left ventricular parameters. The improved endocardial border definition seen with SSFP was not observed at the epicardial border. Improvements in segmentation at the left ventricular epicardial border have been observed with this black-blood sequence. Left ventricular (LV) mass and LV end-diastolic volume (EDV) measurements as well as inter-observer and intra-observer variability were compared between images acquired with a dual inversion BB and SSFP sequence. The mean+/-1 standard deviation (SD) for LV EDV was 178.3+/-52.7 ml measured with SSFP and 158.8+/-62.2 ml with BB. This difference was not statistically significant (p=0.22). For SSFP, the mean value of LV mass was 124.0+/-27.0 g and 147.5+/-37.4 g for BB, a statistically significant difference (p<0.0001). The dual-inversion-recovery BB imaging showed improved reproducibility for LV mass measurements compared with SSFP and improved spatial resolution. For studies requiring LV mass measurements, the dual-inversion-recovery BB sequence offers improved spatial resolution and improved reproducibility to SSFP.

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Section: Discussionmentioning

confidence: 99%

The reproducibility of left ventricular volume and mass measurements: a comparison between dual-inversion-recovery black-blood sequence and SSFP

et al. 2005

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“…Coronary MR-angiography has been demonstrated to be a useful technique for non-invasive visualization of the major epicardial vessels and for detection of coronary artery stenoses [1][2][3][4][5][6][7][8]. However, its clinical utility has been limited by several major obstacles, including compensation for cardiac and respiratory motion and the need for higher spatial resolution.…”

Section: Introductionmentioning

confidence: 98%

3D motion adapted gating (3D MAG): a new navigator technique for accelerated acquisition of free breathing navigator gated 3D coronary MR-angiography

et al. 2005

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This study aimed to evaluate the influence of a new navigator technique (3D MAG) on navigator efficiency, total acquisition time, image quality and diagnostic accuracy. Fifty-six patients with suspected coronary artery disease underwent free breathing navigator gated coronary MRA (Intera, Philips Medical Systems, 1.5 T, spatial resolution 0.9x0.9x3 mm3) with and without 3D MAG. Evaluation of both sequences included: 1) navigator scan efficiency, 2) total acquisition time, 3) assessment of image quality and 4) detection of stenoses >50%. Average navigator efficiencies of the LCA and RCA were 43+/-12% and 42+/-12% with and 36+/-16% and 35+/-16% without 3D MAG (P<0.01). Scan time was reduced from 12 min 7 s without to 8 min 55 s with 3D MAG for the LCA and from 12 min 19 s to 9 min 7 s with 3D MAG for the RCA (P<0.01). The average scores of image quality of the coronary MRAs with and without 3D MAG were 3.5+/-0.79 and 3.46+/-0.84 (P>0.05). There was no significant difference in the sensitivity and specificity in the detection of coronary artery stenoses between coronary MRAs with and without 3D MAG (P>0.05). 3D MAG provides accelerated acquisition of navigator gated coronary MRA by about 19% while maintaining image quality and diagnostic accuracy.

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“…In one single scheduled appointment, CMR may assess morphology, function, myocardial tissue characterization and myocardial perfusion [54].…”

Section: Diagnostic Methodsmentioning

confidence: 99%

“…Still, previous studies comparing the diagnostic value of MPS and CMR [56,57] have shown CMR to perform well. CMR may display perfusion, wall motion and LGE in one appointment [54]. The diagnostic accuracy from CMR first-pass perfusion increases when the information from LGE images is added to the evaluation.…”

Section: Image Qualitymentioning

confidence: 99%

Magnetic Resonance Imaging of the Heart : Image quality, measurement accuracy and patient experience

Ahlander¹

2016

Linköping University Medical Dissertations

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Background: Non-invasive diagnostic imaging of atherosclerotic coronary artery disease (CAD) is frequently carried out with cardiovascular magnetic resonance imaging (CMR) or myocardial perfusion single photon emission computed tomography (MPS). CMR is the gold standard for the evaluation of scar after myocardial infarction and MPS the clinical gold standard for ischemia. Magnetic Resonance Imaging (MRI) is at times difficult for patients and may induce anxiety while patient experience of MPS is largely unknown. Aims: To evaluate image quality in CMR with respect to the sequences employed, the influence of atrial fibrillation, myocardial perfusion and the impact of patient information. Further, to study patient experience in relation to MRI with the goal of improving the care of these patients. Method: Four study designs have been used. In paper I, experimental cross-over, paper (II) experimental controlled clinical trial, paper (III) psychometric crosssectional study and paper (IV) prospective intervention study. A total of 475 patients ≥ 18 years with primarily cardiac problems (I-IV) except for those referred for MRI of the spine (III) were included in the four studies. Result: In patients (n=20) with atrial fibrillation, a single shot steady state free precession (SS-SSFP) sequence showed significantly better image quality than the standard segmented inversion recovery fast gradient echo (IR-FGRE) sequence (I). In first-pass perfusion imaging the gradient echo-echo planar imaging sequence (GREEPI) (n=30) had lower signal-to-noise and contrast–to-noise ratios than the steady state free precession sequence (SSFP) (n=30) but displayed a higher correlation with the MPS results, evaluated both qualitatively and quantitatively (II). The MRIAnxiety Questionnaire (MRI-AQ) was validated on patients, referred for MRI of either the spine (n=193) or the heart (n=54). The final instrument had 15 items divided in two factors regarding Anxiety and Relaxation. The instrument was found to have satisfactory psychometric properties (III). Patients who prior CMR viewed an information video scored significantly (lower) better in the factor Relaxation, than those who received standard information. Patients who underwent MPS scored lower on both factors, Anxiety and Relaxation. The extra video information had no effect on CMR image quality (IV). Conclusion: Single shot imaging in atrial fibrillation produced images with less artefact than a segmented sequence. In first-pass perfusion imaging, the sequence GRE-EPI was superior to SSFP. A questionnaire depicting anxiety during MRI showed that video information prior to imaging helped patients relax but did not result in an improvement in image quality

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MRI in coronary artery disease

Cited by 17 publications

References 49 publications

The reproducibility of left ventricular volume and mass measurements: a comparison between dual-inversion-recovery black-blood sequence and SSFP

The reproducibility of left ventricular volume and mass measurements: a comparison between dual-inversion-recovery black-blood sequence and SSFP

3D motion adapted gating (3D MAG): a new navigator technique for accelerated acquisition of free breathing navigator gated 3D coronary MR-angiography

Magnetic Resonance Imaging of the Heart : Image quality, measurement accuracy and patient experience

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