“…Basically, registration of differently stained serial sections is about transferring the distortions from one kind of staining to another one. Also co-registrations across modalities are a tangent topic to our work, e.g., CT to MRI [93,94,95], serial sections to MRI [96,97,98], or MRI to ultrasound [99]. We distort images from other modalities (similarly to the distortions in serial sections) in order to obtain challenges for testing registration methods with a known ground truth.…”