MRI Findings of Giant Cell Tumors of the Spine

Kwon, Jong Won; Chung, Hye Won; Cho, Eun Yoon; Hong, Sung Hwan; Choi, Sang‐Hee; Yoon, Young Cheol; Yi, Sang Kyu

doi:10.2214/ajr.06.1472

Cited by 80 publications

(48 citation statements)

References 10 publications

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“…10 Curvilinear low signal areas on both T 1 and T 2 weighted images are a common MRI feature of spine GCT (Figures 2d and 5b). This was observed in nine of the ten GCTs studied by Kwon et al 9 and 69% of the tumours in our series. This appearance might correspond to a multiloculated lesion with thickened trabeculae, fibrous septa or haemosiderin deposit.…”

Section: Ct Appearance Of Spine Giant Cell Tumourssupporting

confidence: 69%

“…9 Haemosiderin deposition usually shows nodular, zonal, whorled or diffuse low signal intensity on all sequence images (Figure 1d), 10 and the areas of low signal intensity are exaggerated on T 2 weighted images and more on gradient-recalled echo images for their sensitive of haemosiderin. 10 This phenomenon could support a diagnosis of GCT.…”

Section: Ct Appearance Of Spine Giant Cell Tumoursmentioning

confidence: 95%

“…This appearance might correspond to a multiloculated lesion with thickened trabeculae, fibrous septa or haemosiderin deposit. 9 Focal cystic areas with low signal intensity on T 1 weighted MR images and with high signal on T 2 weighted MR images without internal enhancement are frequent (Figures 1 and 4). These were found in 55% of tumours in our series.…”

Section: Ct Appearance Of Spine Giant Cell Tumoursmentioning

confidence: 98%

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Imaging appearance of giant cell tumour of the spine above the sacrum

Shi¹,

Li²,

Wu³

et al. 2015

BJR

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Giant cell tumour (GCT) of the spine is rarely encountered in daily clinical practice. Most of the tumours occur at the sacrum instead of at the spine above the sacrum, which has been reported to account for 1.3-9.3% of all spine GCTs. This article is a review of our radiological experience of the diagnosis of spine GCT above the sacrum based on 34 patients at a single institution. The purpose of this pictorial review is to highlight the imaging findings of GCT and to provide clues that may distinguish it from other, more common neoplasms.

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Section: Ct Appearance Of Spine Giant Cell Tumourssupporting

confidence: 69%

Section: Ct Appearance Of Spine Giant Cell Tumoursmentioning

confidence: 95%

Section: Ct Appearance Of Spine Giant Cell Tumoursmentioning

confidence: 98%

See 1 more Smart Citation

Imaging appearance of giant cell tumour of the spine above the sacrum

Shi¹,

Li²,

Wu³

et al. 2015

BJR

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“…Although giant cell tumors are benign tumors, they have a 5% rate of local recurrence after wide resection and a 25% recurrence rate after intralesional curettage [5,16,22]. On MRI, an expansile mass with cystic changes typically is seen owing to intratumoral hemorrhage [17], but definitive diagnosis is made histologically by sheets of round mononuclear cells with uniformly interspersed multinucleated osteoclast-type giant cells [19]. None of these features were present in our patient.…”

Section: Discussion and Treatmentmentioning

confidence: 63%

A 33-year-old Man With Low Back Pain

Zhang

Hess

Nielsen

et al. 2014

Clinical Orthopaedics &Amp; Related Research

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A 33-year-old man was evaluated in the clinic for a 9-month history of low back pain. The pain was dull and low grade, worse with activity, occasionally waking him at night. He had no history of antecedent trauma. He had no radiation of pain, focal neurologic symptoms, balance difficulties, or difficulties with fine motor tasks. He had tried aspirin with variable relief, and acupuncture and chiropractic care with no significant improvement. He had no medical conditions, never had spine surgery, and never smoked. He exercised daily doing weight lifting and martial arts, with which his back pain interfered.On physical examination, the patient was generally healthy and appeared well. He had midline tenderness to palpation in his midlumbar spine. The patient had normal strength and ROM, and sensation was intact to light touch throughout. He had normal deep tendon reflexes and no long tract signs. He had normal gait and station.AP and lateral plain films (Fig. 1) of the lumbar spine were obtained initially, followed by CT (Fig. 2) and MRI (Fig. 3); the latter tests were ordered owing to the findings we observed on the plain radiographs.

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“…GCTs of the spine develop in skeletally mature patients during the second to fourth decades of life, and they are more frequently seen in females (4,8). A GCT of the spine can present with pain (often with a radicular distribution), weakness and sensory deficits (9,10).…”

Section: Discussionmentioning

confidence: 99%

Vertebra Plana Caused by a Giant Cell Tumor: A Case Report and Literature Review

Gyu

Shin

Park

et al. 2010

J Korean Soc Radiol

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Vertebra plana is a radiologic diagnosis that indicates complete compression of the vertebral body (1). Although eosinophilic granuloma of the bone is the most frequent benign disease responsible for vertebra plana (2), it can be caused by several pathological conditions. Vertebral plana caused by a giant cell tumor (GCT) has been mentioned in only a few case reports in the English medical literature, and those case reports were without a detailed description (1). To the best of our knowledge, the computed tomography (CT) and magnetic resonance (MR) imaging features of GCT presenting as vertebra plana have seldom been reported in the radiological literature. We report here on the case of

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MRI Findings of Giant Cell Tumors of the Spine

Cited by 80 publications

References 10 publications

Imaging appearance of giant cell tumour of the spine above the sacrum

Imaging appearance of giant cell tumour of the spine above the sacrum

A 33-year-old Man With Low Back Pain

Vertebra Plana Caused by a Giant Cell Tumor: A Case Report and Literature Review

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