MRI and MR spectroscopy findings of the evolution of an intracranial germinoma: A case report

Abstract

Abstract. Intracranial germinomas (IG) are rare tumors that typically occur in the pineal gland and suprasellar region of the brain. IG can be successfully treated with radiation therapy and its recurrence is rare. The present study reports the case of a patient with IG involving the pineal and suprasellar regions. The patient was treated with radiotherapy, achieving significant remission. However, recurrence was discovered 10 months later. The patient was subsequently treated with chemotherapy and radiotherapy, resulting in gradual remission. The patient had recovered 2 months later and was in good health. The entire evolution process, including magnetic resonance (MR) imaging and MR spectroscopy findings, are described herein. The present case suggests that MR spectroscopy may be useful for monitoring the effects of treatment.

Germinomas of the basal ganglia and thalamus: Four case reports

“…Why only germinomas rather than other brain tumors lead to ipsilateral hemiatrophy requires further investigation. Previous reports revealed that susceptibility weighted imaging (SWI) might be more sensitive in detecting early basal ganglia germinoma than conventional MRI, and MR spectroscopy (MRS) was helpful for monitoring the effects of treatment[ 6 , 16 ]. Patient 1 had similar SWI and MRS findings to those in the literature.…”