MRI and CT of adenomatous tumours of the middle ear

Maintz, David; Stupp, C. H.; Krueger, Karsten; Wustrow, J.; Lackner, Klaus-Jürgen

doi:10.1007/s002340000477

Cited by 30 publications

(18 citation statements)

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“…The ossicles are generally embedded in the mass without ossicular or bony erosion. No characteristic differences between the benign and malignant tumors are detectable on a CT [13]. On an MRI, the tumors are isointense or generated a slightly higher signal than white matter on T1-weighted images; there is contrast enhancement.…”

Section: Discussionmentioning

confidence: 99%

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Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series

Saliba

Evrard

2009

Cases Journal

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IntroductionMiddle ear glandular neoplasms are infrequent causes of a middle ear mass. They can have exocrine and/or neuroendocrine differentiation. It is currently thought that these tumors are indistinguishable each from another. Herein, we present a new case of a middle ear glandular neoplasm. Our objective is to review all cases described in the literature in order to identify the clinical features, the gross pathology, the histopathology, the immunohistochemistry, to discuss the differential diagnosis, the treatment, the rate of recurrence, the follow-up, the incidence of metastasis, the prognosis and to present a new classification of middle ear glandular neoplasm.Case presentationMethodsWe performed a MEDLINE database search for MEA-related articles published between 1950 and March 2008. The information from the reports was analyzed.ResultsNinety-four patients with a middle ear adenoma are included in this report. We uncovered 75 patients with a carcinoid tumor and 19 patients with a middle ear adenoma diagnosis; the most common presenting symptom was a conductive hearing loss. Middle ear adenomas are lesions that are typically white, gray or reddish brown. They are grossly vascular and well circumscribed, but not encapsulated, and can entrap and destroy the ossicles. Histologically, the cuboidal to low columnar cells are arranged in a solid, trabecular or glandular architecture. The tumor's cells are immunohistochemically positive for a variety of keratin antibodies and most of them are also positive for neuroendocrine markers. Surgical excision is the treatment of choice. Local recurrence following complete excision is quite uncommon and metastases are rare.ConclusionsOur study and the review of the literature showed adenomas and carcinoid tumors of the middle ear to be essentially indistinguishable benign tumors with metastatic potential. Based on the presence or absence of immunohistochemical markers and metastasis, we have classified these lesions into three types. Complete surgical treatment is recommended with an indefinite follow-up for possible recurrence.

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Section: Discussionmentioning

confidence: 99%

“…On an MRI, the tumors are isointense or generated a slightly higher signal than white matter on T1-weighted images; there is contrast enhancement. On T2-weighted images, the tumors approximate the signal intensity of gray matter [13]. Although the ossicles are visible as signal voids within the tumor, bone erosion could not be assessed.…”

Section: Discussionmentioning

confidence: 99%

Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series

Saliba

Evrard

2009

Cases Journal

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“…Imaging of our patient showed irregular soft tissue lesion in the inner part of left auditory canal just lateral to the tympanic membrane without any bony erosive change. Earlier radiological studies on NAME some patients have showed homogenous, hypodense lesions of temporal bone well limited to the middle ears [8, 12]. The patient in this study underwent a complete excision of the left middle ear tumor along with radical mastoidectomy to avoid future recurrence.…”

Section: Discussionmentioning

confidence: 85%

“Neuroendocrine adenoma of the middle ear with the history of otitis media and carcinoma of the cheek: a case report”

Almuhanna

2014

BMC Res Notes

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BackgroundNeuroendocrine adenomas of the middle ear are rare benign tumors deriving from middle ear mucosal cell with both neuroendocrine and epithelial properties. Approximately one hundred cases have been reported in the literature. Here we report a patient with neuroendocrine adenoma of the middle ear with the history of otitis media; the patient earlier had received radiotherapy for the treatment of basal cell carcinoma.Case presentationA 49- year- old Saudi man presented with a progressive hearing loss and fullness in the left ear with the history of otitis media for which he had undergone myringotomy and ventilating tubes insertion. Earlier at the age of 45 years this patient was given radiotherapy for the treatment of basal cell carcinoma in his cheek. The otoscopy showed a protruded external ear mass obscuring the tympanic membrane. Microscopy and histological examination suggested an endocrine adenoma of the middle ear. The computerized tomography scan of the temporal bone showed an extensive soft tissue mass without any osteolysis. Histological and immunohistochemical examination following surgical excision confirmed the diagnosis of neuroendocrine adenoma of the middle ear.ConclusionA rare case of neuroendocrine adenoma of the middle ear with earlier history of otitis media and carcinoma of the cheek is presented here. Surgical excision of mass resulted in uneventful recovery. Although the etiologic factors leading to the disease is far from clear, the role of radiotherapy given for the treatment of basal cell carcinoma may not be ruled out.

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“…No tienen predominancia de sexo (1)(2)(3)(4) y la edad de aparición puede variar entre los 7 hasta los 80 años (4) . La presentación clínica es inespecífica (5) . El síntoma más común es la hipoacusia unilateral de meses a años de evolución (4,5) .…”

Section: Introductionunclassified

“…La presentación clínica es inespecífica (5) . El síntoma más común es la hipoacusia unilateral de meses a años de evolución (4,5) . Otros síntomas incluyen sensación de plenitud en el oído (1,5) y tinnitus (1,4,5) .…”

Section: Introductionunclassified

Adenoma de oído medio con diferenciación neuroendocrina: Reporte de caso

Esquivel¹,

Leiva

Gaitán³

et al. 2017

RC_UCR-HSJD

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histopatológico fue de adenoma del oído medio con diferenciación neuroendocrina. PALABRAS CLAVEHipoacusia unilateral. Adenoma de oído medio. Diferenciación neuroendocrina. ABSTRACTAdenomas are rare middle ear tumors that derive from the middle ear mucosa and can be easily mistaken for other conditions. Hyams and Michaels first described them in 1976 (1) . They can occur over a wide age range (2) , with no sex predominance (2,3) , and are not characterized by specific symptoms or findings. The most frequent complaints are unilateral hearing loss and ear fullness (2) . We report the case of a male pa-Rev Cl EMed UCR www.revistaclinicahsjd.ucr.ac.cr junio 2017

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MRI and CT of adenomatous tumours of the middle ear

Cited by 30 publications

References 0 publications

Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series

Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series

“Neuroendocrine adenoma of the middle ear with the history of otitis media and carcinoma of the cheek: a case report”

Adenoma de oído medio con diferenciación neuroendocrina: Reporte de caso

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