MRI and CT features of a malignant myoepithelioma of the scrotum: A case report and literature review

Abstract

Malignant myoepithelioma of the scrotum is extremely rare. We report the case of a 51-year-old man with malignant myoepithelioma of the scrotum, wherein computed tomography and magnetic resonance imaging revealed a lobulated soft tissue mass with calcification, cystic component, and solid component with gradual contrast enhancement on dynamic contrast-enhanced scans. The patient presented with scrotal induration, and there was no elevation of tumor markers and no evidence of a metastatic lesion on computed tomography and magnetic resonance imaging. Histopathological examination of the resected scrotal specimen confirmed a well-circumscribed solid tumor with septa, a small area of hemorrhage, and necrosis. The subsequent diagnosis was malignant myoepithelioma of the scrotum. This case shows that scrotal malignant myoepithelioma might appear as a well-defined lobulated mass with cystic regions. We conjecture that the enhancement pattern and apparent diffusion coefficient values can be potential markers for scrotal myoepithelial tumors.

Myoepithelioma-like hyalinizing epithelioid tumor of the foot with OGT-FOX03 fusion gene: Imaging findings, surgical implications, and pathological correlates

“…On T2-weighted imaging with fat suppression all 5 tumors exhibited homogeneous intermediate to high signal intensity [9] . In a case of malignant scrotal myoepithelioma, T2-weighted MRI demonstrated a heterogeneous area of intermediate signal containing low signal reticular structures on T2-weighted imaging [10] . On T1-weighted imaging parts of the tumor had markedly high signal compared to muscle, but no fatty components were visible on fat-saturated sequences [10] .…”

“…In a case of malignant scrotal myoepithelioma, T2-weighted MRI demonstrated a heterogeneous area of intermediate signal containing low signal reticular structures on T2-weighted imaging [10] . On T1-weighted imaging parts of the tumor had markedly high signal compared to muscle, but no fatty components were visible on fat-saturated sequences [10] . Additional documented cases of soft tissue MHETs were consistent with well-defined masses with low to intermediate signal and had internal high signal areas, likely representing internal hemorrhagic areas [11] , [12] , [13] .…”

“…Additional documented cases of soft tissue MHETs were consistent with well-defined masses with low to intermediate signal and had internal high signal areas, likely representing internal hemorrhagic areas [11] , [12] , [13] . With no definitive imaging characteristics to differentiate benign and malignant myoepitheliomas, it was concluded that tissue biopsy was essential to diagnosis [10] .…”

Imaging features of a myoepithelial carcinoma of the nasal cavity: A case report and literature review

“…MRI revealed lobulated tumors with heterogeneous high SI on T2WIs in patients with myoepithelial carcinomas in the nasopharynx, right rhinopharynx, and left submandibular region [ 2 , 3 , 11 ]. In myoepithelial carcinoma of the soft tissue and bone, DWI shows high intensities and low ADC values [ 12 , 13 ]. However, DWI and ADC values for head and neck myoepithelial carcinoma have not been previously reported.…”