MR imaging of dysplasia epiphysealis hemimelica: bony and soft-tissue abnormalities.

Bilateral dysplasia epiphysealis hemimelica of the talus associated with a lower leg intramuscular cartilaginous mass

“…On MRI, both the overgrown bone and the normal bone show heterogeneity on all pulse sequences due to the mixture of tissues (non-mineralised and calcified cartilage, normal cortical bone and yellow marrow) encountered in DEH. There may be oedema within the bone marrow of both the overgrown and normal bone, particularly in the foot and ankle [7]. As shown in our report, and for the first time to the best of our knowledge, a cartilaginous mass may also be identified remote from the epiphysis.…”

“…Subsequently, in 1950 and 1956, Trevor [5] and Fairbank [6] used the terms "tarso-epiphysial aclasis" and "dysplasia epiphysealis hemimelica," respectively, to identify this uncommon skeletal developmental disorder. The reported prevalence of DEH is 1 in 1,000,000, with boys affected up to three times more frequently than girls [7]. The aetiology is still unknown.…”

“…MRI helps define the extent of the cartilaginous component, as well as the effects on surrounding structures (i.e. muscle, tendons, ligaments and menisci) and joint deformity [7]. MRI is the best radiological modality to assess the status of the growth plate and articular cartilage, to establish the diagnosis of DEH at an early stage (before ossification of the lesion), and to assist preoperative planning if surgery is required.…”

A Review of the Actual Knowledge of the Processes Governing Growth and Development of Long Bones

“…[5,6], enriched by the most recent magnetic resonance technology [7][8][9][10]. The definition of the growth vectors on histologic slides documenting the normal physeal development, associated with the findings of traditional x-rays, can provide a hint to integrate imaging data in the light of the actual knowledge of normal and pathologic shape development of the long bones cartilage models.…”

Dysplasia epiphysealis hemimelica of the ankle: a fracture-like rare developmental disorder

“…It is argued that with MRI, it is easier to evaluate the epiphyseal osteochondral growth and its probable effects on adjacent structures, allowing for a better definition of bone and cartilage structures at multiple planes, but scarce reports describing MRI findings of DEH are found in the literature 9 20 21. MRI is indicated as a useful investigation in the early phases of the disease, when a small mass with calcifications inside is observed; this, however, was not the case in our patient 20 21.…”