MR Imaging and Ct of Central Nervous System Tuberculosis in the Patient With Aids

Villoria, M F; Fortea, Fernando; Moreno, Santiago; Muñoz, L; Mañero, Manuela; Benito, Carlos

doi:10.1016/s0033-8389(22)00620-0

Cited by 51 publications

(1 citation statement)

References 58 publications

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“…It is a major public health problem in developing countries, where it remains common [1,2]. It is on the rise in developed countries, especially since the AIDS pandemic [3]. Cerebral intraparenchymal tuberculosis accounts for 10-30% of intracranial expansive processes in developing countries [4][5][6] where it remains endemic and associated with high morbidity and mortality despite advances in imaging and treatment.…”

Section: Introductionmentioning

confidence: 99%

Cerebral abscesses of tuberculosis origin: study of 8 cases at the University Hospital of Conakry

et al. 2020

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Introduction Tuberculosis of the central nervous system (CNS) remains endemic in developing countries with high morbidity and mortality despite advances in imaging and treatment. The objective of our work was to describe the diagnostic and therapeutic difficulties of this pathology in the context of a country with limited health resources. Materials and methods We retrospectively studied 8 cerebral tuberculosis abscess files, collected in the archives of the neurosurgery department of the Conakry University Hospital over a 5-year period (January 2013–December 2017). The diagnosis was made by scanning and by isolation of acid-fast bacilli (AFB) by direct examination of pus. Results Mean age was 33 years (9–56 years), sex, 5H 5 men/3F 3 women. History of pulmonary TB, 3 cases; TB contagious, 5 cases; TST ITR positive, 5 cases; associated visceral TB, 5 cases; HIV positive serology, 2 cases. The clinic was dominated by altered consciousness, 7 cases; focal signs, 7 cases; and fever, 5 cases. The site was hemispherical in 7 cases and one case in the posterior brain fossa. Treatment was medico-surgical in all patients. The evolution was favorable in 3 cases, the neurological sequelae in 3 cases, 2 cases of death, and 2 cases of recurrence. Conclusion Cerebral tuberculous abscesses constitute a medico-surgical emergency. Despite their rarity, morbidity and mortality remains high in the context of developing countries due to diagnostic and therapeutic delays.

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Section: Introductionmentioning

confidence: 99%