MPI in the era of CZT cameras: Absolute numbers are still better than relative figures

Myocardial blood flow reserve and absolute myocardial blood flow for the assessment of patients with coronary artery disease with or without microvascular dysfunction

“…Several studies have recently documented the feasibility of MBF/MFR measurements by CZT technology in comparison to different reference standards, including positron emission tomography (PET) with N 13 H 3 or H 2 O 15 , 1-4 invasive coronary angiography, [5][6][7][8] magnetic resonance imaging, 9 flow fractional reserve, 5,10 and semiquantitative analysis of MPI. 11 Several of the previously cited papers were accompanied by editorial comments [12][13][14][15] which emphasized critical methodological limitations such as most clinical studies have been single site and enrolled a limited number of patients and the methodology is not standardized and varied from center to center.…”