Mp67-01 Sarcopenia as a Predictor of Cancer-Specific And overall Survival After Radical Cystectomy: Is there a Gender Influence?

The association between sarcopenia and bladder cancer-specific mortality and all-cause mortality after radical cystectomy: A systematic review and meta-analysis

“…In total, 145 publications were screened for inclusion and 10 were selected for further review. Of these 10, five publications met the inclusion criteria and were included in the meta-analysis [20][21][22][23][24]. Further details of the selection criteria are shown in Figure 1.…”

“…The quantitative analysis included data from 1447 patients, of whom 453 were classified as sarcopenic and 534 as non-sarcopenic. The discrepancy in the total number of patients is due to the data regarding the number of sarcopenic and non-sarcopenic patients in the Harraz et al [20] abstract being absent. The baseline characteristics for each included study and patient are given in Table 1 [20][21][22][23][24].…”

“…The discrepancy in the total number of patients is due to the data regarding the number of sarcopenic and non-sarcopenic patients in the Harraz et al [20] abstract being absent. The baseline characteristics for each included study and patient are given in Table 1 [20][21][22][23][24]. The median follow-up across the included studies was 40.8 months and included patients were largely similar with regard to median age, tumour stage, and nodal involvement.…”

“…The median follow-up across the included studies was 40.8 months and included patients were largely similar with regard to median age, tumour stage, and nodal involvement. Four of the five studies used CT to determine the crosssectional area of skeletal muscle at the level of the third lumbar vertebrae [21,22,24,25] to define sarcopenia, while Harraz et al [20] used total psoas area (TPA).…”

“…The HR for CSM was available in four of the five studies [20][21][22][23]. On multivariate analysis, there was an increased risk of CSM among sarcopenic compared to non-sarcopenic patients (HR 1.64, 95% CI 1.3-2.08; P < 0.01).…”