“…In a prospective study in 164 patients, C-TRUS/ANNA-guided biopsies were compared to the final pathology of the RP specimen. ANNA/C-TRUS could preoperatively predict the RP Gleason grade of the index lesion in 85 % [ 18 ]. Larger, multicentre trials are underway to support the evidence published so far [ 19 ].…”
Section: Resultsmentioning
confidence: 99%
“… Spec. PPV NPV GSU Sauvain [ 8 ] 282 GSU versus 6–8 biopsies 88 58 72 79 Eisenberg et al [ 9 ] 620 GSU versus RP 59 47 91 11 Zalesky et al [ 12 ] 146 GSU versus RP 8 99 83 59 Kuligowska et al [ 10 ] 544 GSU versus 12 biopsies 41 85 53 72 C-TRUS Walz et al [ 16 ] 28 C-TRUS versus RP 83 64 80 68 Loch et al [ 18 ] 164 C-TRUS versus RP 82 80 Doppler Sauvain [ 8 ] 282 3D-PDU versus 6–8 biopsies 92 72 80 88 Kuligowska et al [ 10 ] 544 …”
Purpose
To investigate the advances and clinical results of the different ultrasound modalities and the progress in combining them into multiparametric UltraSound (mpUS).MethodsA systematic literature search on mpUS and the different ultrasound modalities included: greyscale ultrasound, computerized transrectal ultrasound, Doppler and power Doppler techniques, dynamic contrast-enhanced ultrasound and (shear wave) elastography.Results
Limited research available on combining ultrasound modalities has presented improvement in diagnostic performance. The data of two studies suggest that even adding a lower performing ultrasound modality to a better performing modality using crude methods can already improve the sensitivity by 13–51 %. The different modalities detect different tumours. No study has tried to combine ultrasound modalities employing a system similar to the PIRADS system used for mpMRI or more advanced classifying algorithms.ConclusionAvailable evidence confirms that combining different ultrasound modalities significantly improves diagnostic performance.
“…In a prospective study in 164 patients, C-TRUS/ANNA-guided biopsies were compared to the final pathology of the RP specimen. ANNA/C-TRUS could preoperatively predict the RP Gleason grade of the index lesion in 85 % [ 18 ]. Larger, multicentre trials are underway to support the evidence published so far [ 19 ].…”
Section: Resultsmentioning
confidence: 99%
“… Spec. PPV NPV GSU Sauvain [ 8 ] 282 GSU versus 6–8 biopsies 88 58 72 79 Eisenberg et al [ 9 ] 620 GSU versus RP 59 47 91 11 Zalesky et al [ 12 ] 146 GSU versus RP 8 99 83 59 Kuligowska et al [ 10 ] 544 GSU versus 12 biopsies 41 85 53 72 C-TRUS Walz et al [ 16 ] 28 C-TRUS versus RP 83 64 80 68 Loch et al [ 18 ] 164 C-TRUS versus RP 82 80 Doppler Sauvain [ 8 ] 282 3D-PDU versus 6–8 biopsies 92 72 80 88 Kuligowska et al [ 10 ] 544 …”
Purpose
To investigate the advances and clinical results of the different ultrasound modalities and the progress in combining them into multiparametric UltraSound (mpUS).MethodsA systematic literature search on mpUS and the different ultrasound modalities included: greyscale ultrasound, computerized transrectal ultrasound, Doppler and power Doppler techniques, dynamic contrast-enhanced ultrasound and (shear wave) elastography.Results
Limited research available on combining ultrasound modalities has presented improvement in diagnostic performance. The data of two studies suggest that even adding a lower performing ultrasound modality to a better performing modality using crude methods can already improve the sensitivity by 13–51 %. The different modalities detect different tumours. No study has tried to combine ultrasound modalities employing a system similar to the PIRADS system used for mpMRI or more advanced classifying algorithms.ConclusionAvailable evidence confirms that combining different ultrasound modalities significantly improves diagnostic performance.
“…Moreover, the A N N A / C -T R U S s y s t e m c a n b e t t e r p r e d i c t t u m o r differentiation than random systemic biopsy. In 164 preoperative patients undergoing RP, the SE of ANNA/C-TRUS in predicting the RP Gleason classification of the index lesions was 85% (39).When performing traditional TRUS, the additional use of C-TRUS can assist in the detection and biopsy of cancerous lesions. The combination of C-TRUS and MR can increase the detection rate for high-risk PCa patients (40).…”
Methods for diagnosing prostate cancer (PCa) are developing in the direction of imaging. Advanced ultrasound examination modes include micro-Doppler, computerized-transrectal ultrasound, elastography, contrast-enhanced ultrasound and microultrasound. When two or more of these modes are used in PCa diagnosis, the combined technique is called multiparameter ultrasound (mp-US). Mp-US provides complementary information to multiparameter magnetic resonance imaging (mp-MRI) for diagnosing PCa. At present, no study has attempted to combine the characteristics of different ultrasound modes with advanced classification systems similar to the PIRADS system in mpMRI for the diagnosis of PCa. As an imaging method, mp-US has great potential in the diagnosis of PCa.
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