Motivational control of retrograde amnesia.

Retrieval and Reconsolidation: Toward a Neurobiology of Remembering

“…When this was followed by the amnestic agent, ECS, amnesia was obtained (Lewis et al 1972;Lewis and Bregman 1973). Numerous control procedures assured that the specific cues associated with the original learning were essential to the effect and not merely a reinstatement of an emotional or motivational state, as had been suggested by other investigators Robbins and Meyer 1970). Hypothermia-induced amnesia for a well-trained task was obtained after exposure of the rat to either the unconditioned stimulus (UCS) (foot shock) or the context and UCS, immediately before the amnestic treatment (Mactutus et al 1979;Richardson et al 1982).…”

Retrograde amnesia for previously acquired Pavlovian conditioning: UCS exposure as a reactivation treatment

“…On the other hand, a second FS has been shown to extend the temporal gradient of ECS, suggesting RA for earlier acquisition (Schneider & Sherman, 1968). Furthermore, although they employed a somewhat atypical paradigm, Meyer and his colleagues (Howard, Glendenning, & Meyer, 1974;Robbins & Meyer, 1970) demonstrated that reexposure to a FS-escape contingency shortly prior to ECS results in suppression of memory for an earlier acquired discriminative shock-escape habit. Thus, these mixed findings leave ambiguous the status of the vulnerability of old memory following NCFS.…”

The cerebral cortex: Its roles in memory storage and remembering

“…Hence, we undertook aseries of studies which showed that if rats are trained on several tasks, and the tasks are learned for different incentives, a single ECT that is given immediately foIlowing completion of training on the last task will suppress performance of an earlier task if, and only if, the same incentives were employed for training on both the earlier and the last task (Howard, Glendenning, & D. R. Meyer, 1974;Howard & D. R. Meyer, 1971;Robbins & D. R. Meyer, 1970).…”