Mosaicism in the skin: lumping or splitting?

Abstract

Linked Article: Kuentz et al. Br J Dermatol 2017; 176:204–208.

An unexpected coexistence of two epidermal naevi on the scalp: Naevus comedonicus and naevus sebaceous

“…Based on these findings, Has suggested FGFR2 mutations may be underlying cause of different types of epidermal naevi, depending on the involved cell. 9 Considering these reports and suggestions, we may speculate the coexistence of naevus sebaceus and naevus comedonicus in our patient may be due to FGFR2 mutation which resulted with differentiation towards sebaceous glands and follicular structures. More reports are necessary to substantiate this association.…”

Comedonicus variant of keratinocytic epidermal naevus—Comment on ‘An unexpected coexistence of two epidermal naevi on the scalp: Naevus comedonicus and naevus sebaceous’

“…Additional Supporting Information may be found online in Supporting Information: Table S1. Corticosteroid Conversion Table (5)(6)(7)(8). doi: 10.1111/ajd.13415…”

Fifty‐two words for snow: dermatologists naming epidermal naevi

“…4 Microdissection and genetic analysis of epidermal naevi are not yet widely available clinical tests, although clinical and histological criteria are easily applied for the purposes of diagnosis. A tendency to 'lump' KEN and NS together has made it difficult to analyse the frequency of various associated findings, thus making prognostication of the clinical course more difficult.…”