Mortality in Alzheimer's disease: a comparative prospective Korean study in the community and nursing homes

Suh, Guk-Hee; Yeon, Byeong Kil; Shah, Ajit; Lee, Jun-Young

doi:10.1002/gps.1256

Cited by 49 publications

(31 citation statements)

References 24 publications

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“…A US study of 883 nursing home residents found that one per cent of people with dementia were recorded as having a life expectancy of less than six months, but 71% of them died during this period (Mitchell et al, 2004a). A Korean study (Suh et al, 2004) tested the hypothesis that mortality in people with dementia is higher in care homes than in the community and found no difference in mortality rate. Predictors of death were age, global deterioration, duration of disease, the presence of hallucinations, wandering and depression.…”

Section: Predicting the Approach Of Death For People With Dementiamentioning

confidence: 99%

End of life care for community dwelling older people with dementia: an integrated review

Goodman

Evans

Wilcock

et al. 2009

Int J Geriat Psychiatry

106

102

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Objective: To review the evidence for end-of-life care for community dwelling older people with dementia (including those resident in care homes). Design: An integrated review synthesised the qualitative and quantitative evidence on end-of-life care for community dwelling older people with dementia. English language studies that focused on prognostic indicators for end-of-life care, assessment, support/relief, respite and educational interventions for community dwelling older people with dementia were included. A user representative group informed decisions on the breadth of literature used. Each study selected was screened independently by two reviewers using a standardised check list. Results: Sixty eight papers were included. Only 17% (12) exclusively concerned living and dying with dementia at home. Six studies included direct evidence from people with dementia. The studies grouped into four broad categories: Dementia care towards the end of life, palliative symptom management for people with dementia, predicting the approach of death for people with dementia and decision-making. The majority of studies were descriptive. The few studies that developed dementia specific tools to guide end of life care and outcome measures specific to improve comfort and communication, demonstrated what could be achieved, and how much more needs to be done. Conclusions: Research on end-of-life care for people with dementia has yet to develop interventions that address the particular challenges that dying with dementia poses. There is a need for investigation of interventions and outcome measures for providing end-of-life care in the settings where the majority of this population live and die.

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Section: Predicting the Approach Of Death For People With Dementiamentioning

confidence: 99%

End of life care for community dwelling older people with dementia: an integrated review

Goodman

Evans

Wilcock

et al. 2009

Int J Geriat Psychiatry

106

102

View full text Add to dashboard Cite

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“…Comorbid depression in patients with AD has been associated with decreased quality of life (Shin et al, 2005), increased need for institutionalization (Steele et al, 1990), greater health care utilization (Kunik et al, 2003), higher mortality rates (Suh et al, 2005) and decreasing caregiver's well being (Kerkstra et al, 1999;Shin et al, 2005). These serious consequences ask for the development of strategies for prevention, early recognition and intervention for depression in AD.…”

Section: Introductionmentioning

confidence: 96%

The relationship between severity of Alzheimer's disease and prevalence of comorbid depressive symptoms and depression: a systematic review

Verkaik

Nuyen

Schellevis

et al. 2007

Int J Geriat Psychiatry

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“…Suh et al [31] compared a nursing home AD cohort with a community-based cohort and reported a longer duration of illness at study entry, a lower functional ability, a more advanced dementia and a higher prevalence of sensory impairment of nursing home residents. However, there was no statistically signifi cant difference in mortality rates between those who continued to be cared for at home and AD patients in nursing homes [31] . This is in line with our fi ndings.…”

Section: Other Predictors Of Death In the Entire Populationmentioning

confidence: 99%

Incident Dementia Cases and Mortality

Gühne¹,

Matschinger²,

Angermeyer³

et al. 2006

Dement Geriatr Cogn Disord

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Mortality caused by dementia has mainly been examined in population-based studies relying on prevalent cases. This study aims to investigate the impact of incident dementia on mortality as well as to identify factors influencing the course of dementia and those predicting early death in demented individuals. A representative community sample of 1,692 individuals aged 75 years and over was examined by neuropsychological testing in a four-wave study. Data were analyzed with the Cox proportional hazards model after making necessary adjustments for potential covariates. At the third follow-up 51% of the incident demented and 19% of the participants without dementia had died. The mean survival time was 3.1 years (95% CI = 2.8–3.4) for the demented subjects and 4.0 years (95% CI = 3.9–4.0) for those without dementia (p < 0.001). In the total sample, the relative risk of dying after developing dementia was estimated to be 2.4 (95% CI = 1.6–3.6) with age, sex, education, co-morbidity, and institutionalization being taken into consideration. Those persons with incident dementia who died had a more severe dementia. Population-based studies relying on incident cases are especially valuable in describing course and outcome of dementia. Studies relying on prevalent cases and clinical samples tend to overestimate mortality and propose course-modifying factors that are challenged by studies relying on incident cases.

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Mortality in Alzheimer's disease: a comparative prospective Korean study in the community and nursing homes

Abstract: This study does not support the hypothesis of a higher AD mortality rate in nursing homes.

Cited by 49 publications

References 24 publications

End of life care for community dwelling older people with dementia: an integrated review

End of life care for community dwelling older people with dementia: an integrated review

The relationship between severity of Alzheimer's disease and prevalence of comorbid depressive symptoms and depression: a systematic review

Incident Dementia Cases and Mortality

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