Mortality from eating disorders?a 5- to 10-year record linkage study

Re-examining premature mortality in anorexia nervosa: A meta-analysis redux

“…However, because follow-up time was not a significant predictor of SMR after the exclusion of two outliers, we do not believe that our generalizability was adversely affected. We also calculated the SMR using expected rates for females aged 15-34 in the general population, which was representative of most patients enrolled in the studies included, but not all (on average, only 4% of patients [range: 0-18%] were male, and mean age at entry was 21 years [range: [14][15][16][17][18][19][20][21][22][23][24][25][26][27]). Additionally, because most studies included women aged 15-34, future mortality research is needed in younger, older, and male populations with AN.…”

Mortality in anorexia nervosa – a look back at and beyond one of the most cited papers in the field

“…age, inpatient versus outpatient subjects, and first contact or newly referred patient versus chronic cases or patients who have repeatedly sought help). Looking at the majority of studies dealing with mortality in AN published after 1995, we observe a relative wide range of SMR: 7 studies reported a SMR for AN of 10 or higher (Birmingham, Su, Hlynsky, Goldner, & Gao, 2005;Hoang, Goldacre, & James, 2014;Huas et al, 2011;Keel et al, 2003;Lee, Chan, & Hsu, 2003;Rosling, Sparén, Norring, & von Knorring, 2011;Suokas et al, 2013); 11 studies reported a SMR higher than 5 (Button, Chadalavada, & Palmer, 2010;Crow, Praus, & Thuras, 1999;Emborg, 1999;Fichter, Quadflieg, & Hedlund, 2006;Franko et al, 2013;Gueguen et al, 2012;Herzog et al, 2000;Löwe et al, 2001;Møller-Madsen, Nystrup, & Nielsen, 1996;Papadopoulos, Ekbom, Brandt, & Ekselius, 2009;Signorini et al, 2007); 3 studies reported a SMR between 1 and 4 (Crisp, 2006;Crow et al, 2009;Lindblad, Lindberg, & Hjern, 2006); 1 study reported a SMR below 1 (Korndörfer et al, 2003); and 4 studies reported 0 mortality (Halvorsen, Andersen, & Heyerdahl, 2004;Herpertz-Dahlmann et al, 2001;Strober, Freeman, & Morrell, 1997;Wentz, Gillberg, Anckarsater, Gillberg, & Rastam, 2009). Among the studies that reported very low or non-existent mortality rates, we can see a preponderance of relatively small sample sizes investigating adolescents with AN.…”

“…The authors found no deaths among individuals below the age of 15, but elevated mortality rates among those (including females and males) aged 15-25 and 25-44 years, with the highest SMR of 14 (95% CI: 9.2-18.8) in the older age group. Papadopoulos et al (2009), Birmingham et al (2005, Erdur et al (2012), Huas et al (2011), andCrow et al (1999) all report average mean ages of death ranging from 34.2 to 37 years (note that some of the samples are pure AN samples, while some are mixed ED samples).…”

Anorexia nervosa

“…Die Prognose der AN konnte durch die Etablierung einer multimodal vorgehenden Psychotherapie deutlich verbessert werden.In einer Multizenterstudie zeigten im Langzeitverlauf 36% der Patientinnen eine Voll-und weitere 55% eine Teilremission [15].Trotzdem zählt die in der Literatur angegebene Letalität mit 5-16% zu den höchsten bei psychiatrischen Erkrankungen [8,10,11,17]. Neuere Studien zeigen Letalitätsraten eher im unteren Bereich dieser Spanne [5,17].…”