Mortality following the first hip fracture in Norwegian women and men (1999–2008). A NOREPOS study

Omsland, Tone Kristin; Emaus, Nina; Tell, Grethe S.; Magnus, Jeanette H.; Ahmed, Luai A.; Holvik, Kristin; Forsmo, Siri; Gjesdal, Clara Gram; Schei, Berit; Vestergaard, Peter; Eisman, John A.; Falch, Jan A.; Tverdal, Aage; Søgaard, Anne Johanne; Meyer, Haakon E

doi:10.1016/j.bone.2014.02.016

Cited by 130 publications

(120 citation statements)

References 30 publications

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“…Accordingly, the risk of osteoporotic fractures and their associated costs is rising rapidly due to aging population [3]. In the elderly, hip fractures are closely associated with mortality [4]. Hormone deficiency is known to impair cancellous metaphyseal and reduce BMD in humans and animals.…”

Section: ------------------------------------------------------------mentioning

confidence: 99%

Effect of Dihuang rougui decoction on ovariectomyinduced osteoporosis in rats

Du¹,

Wu²,

Ma³

et al. 2018

Trop. J. Pharm Res

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Section: ------------------------------------------------------------mentioning

confidence: 99%

Effect of Dihuang rougui decoction on ovariectomyinduced osteoporosis in rats

Du¹,

Wu²,

Ma³

et al. 2018

Trop. J. Pharm Res

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“…One-year mortality in hip fracture patients was almost 5-fold higher in men and 3-fold higher in women compared to the general Norwegian population. During 1999-2008, 23,353 patients above 50 years of age died within a year after the fracture, constituting 29% of all hip fracture patients [50]. The excess mortality was highest during the first two weeks, but was still present more than 10 years after the fracture [50].…”

Section: Forearm Fracturementioning

confidence: 99%

Cohort profile: Norwegian Epidemiologic Osteoporosis Studies (NOREPOS)

Søgaard

Meyer

Emaus

et al. 2014

Scand J Public Health

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AimsThis paper describes the history, purpose, data collection and contributions in the research collaboration Norwegian Osteoporosis Epidemiologic Studies (NOREPOS). Methods NOREPOS encompasses almost ResultsMain findings include: Every hour a Norwegian suffers a hip fracture; hip fracture incidence rates declined after 1999; only 16% of patients used anti-osteoporosis drugs one year after hip fracture; 25% of patients died within one year after the fracture; 12% suffered a new hip fracture within 10 years; rural dwellers had lower hip-and forearm fracture incidence than city dwellers; magnesium in tap water may be protective whereas bacterial contamination, cadmium and lead may be harmful to bone health; low serum vitamin D and E levels were associated with higher hip fracture risk; vitamin A was not associated with fracture risk; and abdominal obesity increased the risk of hip fracture when BMI was accounted for. Conclusion

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“…Presently the hormone whose deficiency is widely believed to be linked to osteoporosis in post-menopausal women is estrogen [4]. Osteoporosis is twice as common in women as in men, and approximately one in three women over 50 years old experience an osteoporotic fracture [5].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Epimedium brevicornum Maxim extract for anti-osteoporosis activity in rats

Jianqing¹,

Zhuang²,

Wang³

et al. 2017

Trop. J. Pharm Res

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Purpose: To evaluate the therapeutic effect of Epimedium brevicornum Maxim. extract (EBME) on ovariectomy-induced osteoporosis in rats. Methods:The rats were divided into six experimental groups, viz, control (group 1) ALP), urinary calcium (U-Ca), urinary phosphorus (U-P), urinary creatinine (U-SCr) and osteocalcin (OC) levels. Result:The results showed that the BMD decrease induced by OVX in 4LV and femur was significantly mitigated by high dose of EBME. EBME also protected the trabecular microarchitecture against OVXassociated deterioration, evidenced by decreased bone turnover marker levels in 4LV at high EBME dose. 3.7 ± 0.2), trabecular thickness 0.082 ± 0.011), and trabecular spacing 0.17 ± 0.01)

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Mortality following the first hip fracture in Norwegian women and men (1999–2008). A NOREPOS study

Cited by 130 publications

References 30 publications

Effect of <i>Dihuang rougui</i> decoction on ovariectomyinduced osteoporosis in rats

Effect of <i>Dihuang rougui</i> decoction on ovariectomyinduced osteoporosis in rats

Cohort profile: Norwegian Epidemiologic Osteoporosis Studies (NOREPOS)

Evaluation of <i>Epimedium brevicornum</i> Maxim extract for anti-osteoporosis activity in rats

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