Mortality after surgery in Europe

Pupelis, Guntars; Vanags, Indulis

doi:10.1016/s0140-6736(13)60159-2

Cited by 8 publications

(2 citation statements)

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“…Our study on mortality after non-cardiac surgery in Europe has been widely debated [112][113][114][115][116][117][118][119]. The validity of the database has been questioned, especially from countries with a high intra-hospital mortality rate.…”

Section: Paper Ii: European Surgical Outcome Study (Eusos)mentioning

confidence: 99%

Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine

Jammer

Wickboldt

Sander

et al. 2015

European Journal of Anaesthesiology

577

222

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There is a need for large trials that test the clinical effectiveness of interventions in the field of perioperative medicine. Clinical outcome measures used in such trials must be robust, clearly defined and patient-relevant. Our objective was to develop standards for the use of clinical outcome measures to strengthen the methodological quality of perioperative medicine research. A literature search was conducted using PubMed and opinion leaders worldwide were invited to nominate papers that they believed the group should consider. The full texts of relevant articles were reviewed by the taskforce members and then discussed to reach a consensus on the required standards. The report was then circulated to opinion leaders for comment and review. This report describes definitions for 22 individual adverse events with a system of severity grading for each. In addition, four composite outcome measures were identified, which were designed to evaluate postoperative outcomes. The group also agreed on standards for four outcome measures for the evaluation of healthcare resource use and quality of life. Guidance for use of these outcome measures is provided, with particular emphasis on appropriate duration of follow-up. This report provides clearly defined and patient-relevant outcome measures for large clinical trials in perioperative medicine. These outcome measures may also be of use in clinical audit. This report is intended to complement and not replace other related work to improve assessment of clinical outcomes following specific surgical procedures.

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Section: Paper Ii: European Surgical Outcome Study (Eusos)mentioning

confidence: 99%

Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine

Jammer

Wickboldt

Sander

et al. 2015

European Journal of Anaesthesiology

577

222

View full text Add to dashboard Cite

show abstract

“…There were wild fluctuations in perioperative mortality that should have alerted the authors as to the unreliability of their data collection method, with mortality ranging from an anticipated rate of 1.2 % to as high as 21.5 % in some countries. The article provoked a string of letters [23][24][25][26][27]. The actual mortality rates are more likely to be in the range of 0.5-1.2 %.…”

Section: Misinterpreting Perioperative Mortalitymentioning

confidence: 99%