Morphometric Features of the Structural Components of the Hemomicrocirculatory Bed in the Perivulnar Region of the Caecum in Wound Defect Sutured With Polyfilament Suture Material

Abstract

The aim: The study focuses on the morphometric features specification concerning the structural components of the hemomicrocirculatory bed of the perivulnar region of the cecum in rabbits when suturing a wound defect with synthetic polyfilament surgical suture Vicryl. Materials and methods: The research was carried out on rabbits (n = 30: 5 animals made up the control group and 25 animals made up the experimental group) and included surgery based on the method of surgical intervention on the large intestine patented by the authors, which was performed in the conditions of the operating room at the Department of Clinical Anatomy and Operative Surgery. When determining the main morphometric parameters, we took biopsy specimens of the cecum and used paraffin and epoxy resin embedding considering the generally accepted methods. Results: The study determined that the implantation of Vicryl surgical suture material in the tissues of the cecum became a trigger for the formation of active inflammatory focus and occurrence of leukocyte infiltrate in the perivulnar region. Conclusions: Arterioles, as a resistive link, capillaries, as an exchange link and venules, as a capacitive link in the hemomicrocirculatory bed, actively participate in response to the inflammatory process and formation of a connective tissue scar. The process of structural organization of microvessels begins in the formed granulation tissue in the perivulnar region of the cecum starting from the 14th day of the experiment.

Structural Organization of the Adrenal Glands Medulla of Rats in Normal and After Influence of Food Additive Complex

“…According to literature sources, the response of HMCB to external and internal environmental factors is quite specific. Therefore, during the morphological study of HMCB elements, we analyzed the total diameter of arteries, venules and capillaries, the lumen of these vessels and the average thickness of their walls [5][6]. In particular, we paid attention to the uneven thick- ening of the walls of arterioles, venules and capillaries, which manifested itself in the form of swelling and disorganization of the connective tissue surrounding these vessels.…”

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Immunohistochemical Characteristics of Structural Changes in the Cortex and Medulla of the Adrenal Glands Under the Influence of a Food Additive Complex

“…Food additives are needed to maintain the attractive appearance and long-term food storage. More than a thousand existing food additives can be found on supermarket shelves without the consumer even knowing about their existence [5][6]. Not all manufacturers list additional harmful food additives in their products.…”

Analysis of early morphological and functional perivulnar changes in the mucosa of the cecum after suturing with different surgical threads

“…The scientific achievements of modern medicine make it possible to introduce more and more new means and treatment methods into surgical practice. Currently, the effectiveness of surgical interventions depends not only on the surgeon's professionalism but also on the quality of material and technical support, particularly on the properties of the suture material [9,10,15]. In abdominal surgery, particularly in pediatric surgery, the correct choice of suture material is the key to successful and rapid wound healing [13].…”