Morphometric and morphologic parameters of the heart in healthy <i>Alouatta guariba clamitans</i> (Cabrera, 1940)

Charlier, Murilo Gomes de Soutello; Filippi, M; Girotto, Carolina Hagy; Ribeiro, Vanessa Lanes; Teixeira, Carlos Roberto; Lourenço, Maria Lúcia Gomes; Vulcano, Luiz Carlos

doi:10.1111/jmp.12320

Cited by 2 publications

(2 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, VHS has been measured in other NHP species by using this same method. 7,14,15,19,20,22,25,26,32,34 The reference intervals obtained in our current study closely resemble those for VHS in other NHP species, including owl monkeys (Aotus spp.) common marmosets (Callithrix jacchus), spider monkeys (Ateles fusciceps), goeldi monkeys (Callimico goeldii), tufted capuchins (Cebus apella), African green vervet monkeys (Chlorocebus sabaeus), howler monkeys (Aloutta guariba clamitans), Japanese macaques (Macaca fuscata), and squirrel monkeys (Saimiri spp.).…”

Section: Discussionsupporting

confidence: 76%

Vertebral Heart Score in Rhesus Macaques (Macaca mulatta): Generating Normal Reference Intervals and Assessing its Validity for Identifying Cardiac Disease

Williams¹,

Ueda²,

Stern³

et al. 2020

j am assoc lab anim sci

View full text Add to dashboard Cite

Vertebral heart scoring (VHS) is a semiquantitative method to assess the presence and severity of cardiomegaly by usingthoracic radiographs. VHS in rhesus macaques (Macaca mulatta) has not been validated or used routinely in the clinical orresearch setting. We hypothesized that rhesus macaques with cardiac disease diagnosed by using echocardiography wouldhave higher VHS than animals without cardiac disease. A total of 150 rhesus macaques were enrolled in this study. All animalsunderwent echocardiography and thoracic radiography (right lateral [RL], dorsoventral [DV], and ventrodorsal [VD] views).According to echocardiography, 121 rhesus macaques had no cardiac disease and were used to establish reference intervalsfor VHS. The remaining 29 macaques had hypertrophic cardiomyopathy (n = 20) or other cardiac disease (n = 9). Resultsshowed that VHS of RL and VD views were significantly higher in macaques with any of the identified cardiac diseases andin the cardiac disease group that excluded hypertrophic cardiomyopathy. VHS of animals with HCM was not significantlydifferent than that of control animals. In the RL view, VHS was moderately accurate for predicting the presence of cardiacdisease, with an AUC of 0.71 and an optimal cut-off value of 10.25 (sensitivity: 62%, specificity: 77%). In the VD view, VHSwas a mildly accurate test for cardiac disease, with an AUC of 0.654 and an optimal cut-off value of 10.65 (sensitivity, 66%;specificity, 63%). Study results indicated that VHS could be a useful screening tool for clinically identifying rhesus macaqueswith cardiac disease. However, VHS is unlikely to replace echocardiographic examination for determining the presence, type,and severity of cardiac disease in this species.

show abstract

Section: Discussionsupporting

confidence: 76%

Vertebral Heart Score in Rhesus Macaques (Macaca mulatta): Generating Normal Reference Intervals and Assessing its Validity for Identifying Cardiac Disease

Williams¹,

Ueda²,

Stern³

et al. 2020

j am assoc lab anim sci

View full text Add to dashboard Cite

show abstract

“…Methods for assessing cardiac enlargement using chest radiographs include vertebral heart size (VHS) and cardiothoracic ratio (CTR). There are many reports on VHS in dogs 12,13 and monkeys, such as Japanese macaques 14 , rhesus macaques 15 , spider monkeys 16 , common marmosets 17 , geldi monkeys 18 , squirrel monkeys 19 , and howler monkeys 20 ; however, CTR has been mostly reported in humans 21 . Reference intervals for VHS have been reported in rhesus macaques.…”

mentioning

confidence: 99%

The effect of different body positions on the cardiothoracic ratios obtained by chest radiography in Japanese macaques (Macaca fuscata) and rhesus macaques (Macaca mulatta)

Sawada

Kaneko

Morimoto

et al. 2022

J of Medical Primatology

View full text Add to dashboard Cite

Background Although some studies have reported cardiac diseases in macaques, an adequate screening method for cardiac enlargement has not yet been established. This study aimed to evaluate the positioning of macaques for radiographs and establish reference intervals for the cardiothoracic ratio (CTR). Materials and Methods We developed a device for chest radiography in the sitting position and performed chest radiography in 50 Japanese and 48 rhesus macaques to evaluate the CTR and chest cavity size. Results In Japanese and rhesus macaques, the thorax height was significantly larger, the heart width was significantly smaller, and the mean CTR was significantly smaller in the sitting position than in the prone position. The reference intervals for CTR in the sitting position were 51.6 ± 4.6% and 52.2 ± 5.1% in Japanese and rhesus macaques, respectively. Conclusion Thoracic radiographic images obtained in a sitting position resulted in a smaller CTR and a larger thorax height, which could be useful for detecting pulmonary and cardiac abnormalities.

show abstract

Morphometric and morphologic parameters of the heart in healthy Alouatta guariba clamitans (Cabrera, 1940)

Abstract: Exam techniques were akin the ones used in humans. Doppler echocardiographic, radiographic, electrocardiographic and clinical parameters for howler monkey were described and correlated. The results have shown profiles of cardiovascular function and structure of A. g. clamitans.

Cited by 2 publications

References 11 publications

Vertebral Heart Score in Rhesus Macaques (Macaca mulatta): Generating Normal Reference Intervals and Assessing its Validity for Identifying Cardiac Disease

Vertebral Heart Score in Rhesus Macaques (Macaca mulatta): Generating Normal Reference Intervals and Assessing its Validity for Identifying Cardiac Disease

The effect of different body positions on the cardiothoracic ratios obtained by chest radiography in Japanese macaques (Macaca fuscata) and rhesus macaques (Macaca mulatta)

Contact Info

Product

Resources

About