Morphologische Betrachtungen des Zwischenhirn-Hypophysen-Systems beim Hund nach Zufuhr von Oxytocin und Vasopressin

‘Ultrashort’ Feedback Control of Follicle-Stimulating Hormone-Releasing Factor Secretion

“…Administration of oxytocin and vasopressin to normal animals has been shown to reduce the activity of neuro secretory cells of the paraventricular and of the supraopdc nuclei [Mietkiewski and K ozik, 1965;O rf, 1966] and to increase the amount o f Gomori-positive material at the level o f the median emi nence [De Wied et a l., 1964;O rf, 1966]. A considerable inactivation of acid phosphatase in the anterior hypothalamus has been observed following treatment with vasopressin [Hiroshige et a l., 1966].…”

Morphological changes in diencephalic nuclear areas after administration of anterior pituitary hormones in the dog, guinea-pig and rabbit

“…Prolonged adm inistra tion of sexual, adrenocortical and thyroid hormones produces a feedback-reaction causing diminished secretion of the corresponding glandotrophic hormones and also brings about morphological changes, histologically discernible, in the glandular parenchym a of the adenohypophysis. In sim ilar manner, protracted adm inistration of posterior-lobe horm ones leads to noticeable morphological adaptive reactions in the magnocellular hypothalam us-neurohypophyseal system (Orf [1966]). On the basis of these empirical findings it was thus to be conjectured th a t long-term applica tion of anterior lobe hormones would bring about morphological changes in the parvocellular hypothalam ic nuclei controlling adenohypophyseal activity.…”