Morphological variability of the subcallosal area of man

Spasojević, Goran; Malobabić, Slobodan; Suscevic, Dusan; Stijak, Lazar; Nikolić, Valentina; Gojković, Igor

doi:10.1007/s00276-010-0689-2

Cited by 5 publications

(3 citation statements)

References 12 publications

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“…This allowed us to empirically estimate, in the brain of a disease-free individual, the number of detected 10-voxel differences in each cortical and subcortical region for different corrected voxel-wise significance thresholds. Based on previous analyses of neuroanatomical variability in the healthy population (Fornito et al, 2008;Good et al, 2001;Pruessner et al, 2002;Salmond et al, 2002;Spasojević et al, 2011) we hypothesized a large number of significant differences in single subjects relative to their control group when using a standard statistical threshold of p b 0.05 (corrected for multiple comparisons across the whole brain). However, these differences would be minimized with the use of more conservative statistical thresholds such as p b 0.01 (corrected) and p b 0.001 (corrected).…”

Section: Introductionmentioning

confidence: 99%

When the single matters more than the group: Very high false positive rates in single case Voxel Based Morphometry

et al. 2013

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Section: Introductionmentioning

confidence: 99%

When the single matters more than the group: Very high false positive rates in single case Voxel Based Morphometry

et al. 2013

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“…39 This is made even more confusing by using the Brodmann area classification to describe this region since Brodmann areas are defined by cytoarchitecture rather than topography and function connected to macroscopic and radiologically identifiable surface anatomy. 24 The subcallosal prefrontal region consists of two limbic cortical areas with their associated white matter: the subcallosal extension of the cingulate gyrus and the paraterminal gyrus 39 The anatomy here is easiest to understand when considering the embryology of the limbic lobe. The limbic lobe consists of two curved bands, an inner and outer arch, which surround the diencephalon and basal ganglia.…”

Section: Discussionmentioning

confidence: 99%

Hypoactivity in the Paraterminal Gyrus Following Bilateral Anterior Capsulotomy

et al. 2019

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Objective: Bilateral anterior capsulotomy (BAC) is one of the ablative neurosurgical procedures used to treat major depressive disorder or obsessive-compulsive disorder when all other therapies fail. Tristolysis, a reduction in sadness, is the most striking clinical effect of BAC and is seen in the first 1 to 2 weeks after surgery. This retrospective study measured regional cerebral blood flow (rCBF) following surgery to identify which cortical regions were impacted and could account for this clinical effect. Methods: All patients had their capsulotomies done in Vancouver by the same team. Pre- and postoperative single-photon emission computed tomography perfusion scans were analyzed for 10 patients with major depressive disorder and 3 with obsessive-compulsive disorder. rCBF was measured semiquantitatively by calculating the ratio between an identified region of interest and a whole brain reference area. Results: Decreased rCBF was found in the paraterminal gyri. Increased rCBF was found in the dorsolateral prefrontal cortices and in the left lateral temporal lobe. Conclusions: BAC causes hypoactivity in the paraterminal gyri and is the most likely explanation for its tristolytic effect, suggesting that the paraterminal gyrus is the limbic cortical locus for the emotion of sadness. Increased activity in the dorsolateral prefrontal cortices may be occurring via connectional diaschisis, and suppression by overactive paraterminal gyri during depression may account for some of the neurocognitive deficits observed during depressive episodes.

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“…Therefore, although still under debate, many terms in the literature may have the same meaning as the term subcallosal gyrus, including the paraterminal gyrus, precommissural septum, and peduncle of the corpus callosum (Fig. 1) [3,4].…”

Section: Relevant Surgical Anatomymentioning

confidence: 99%

How I do it: surgical resection of a subcallosal gyrus cavernous malformation by a contralateral anterior interhemispheric approach

et al. 2021

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Background Cavernous malformation (CM) of the subcallosal gyrus is extremely rare, and due to its close relationship with the lateral ventricle's frontal horn, it may be misdiagnosed as caudate head or ventricle CM. Method This video shows a rare case of subcallosal gyrus CM successfully cured by a contralateral anterior interhemispheric approach. Conclusion We hope this case provides new insights into anatomical knowledge and surgical approach techniques for subcallosal lesions.

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Morphological variability of the subcallosal area of man

Abstract: Accurate neuroanatomical localization requires exact determination of boundaries of subcallosal area. Therefore, standardized criteria were proposed for definition of subcallosal area.

Cited by 5 publications

References 12 publications

When the single matters more than the group: Very high false positive rates in single case Voxel Based Morphometry

When the single matters more than the group: Very high false positive rates in single case Voxel Based Morphometry

Hypoactivity in the Paraterminal Gyrus Following Bilateral Anterior Capsulotomy

How I do it: surgical resection of a subcallosal gyrus cavernous malformation by a contralateral anterior interhemispheric approach

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