Morphological Study of Intestinal Polyps With Clinicopathological Correlation - 2 Years Observational Study at a Tertiary Care Centre of South India

Abstract

BACKGROUNDPolyps of the intestine are common specimens and do not have symptoms unless they cause obstruction or bleed. 1 There are many types of intestinal polyps. Among all polyps, most frequently occurring are adenomatous polyps. Adenomas are considered precursor lesions to invasive carcinoma. Colorectal cancer stands second to lung cancer as the most common cause of cancer mortality. The basic aim of management of patients with adenomatous polyps in the large bowel remains to prevent the development of cancer by detection and removal of precancerous lesions.The objective of this study is to classify intestinal polyps and identify prevalence of each morphologic type. To study the gross and histopathological features and to correlate with clinical data.

Polypoidal lesions of the gastrointestinal tract

“…11 The age of the patients ranged from 7 to 84 years with a mean age of 50 years. This finding is in accordance with studies of Chitturi et al 3 and Manakkad et al 7 The age of the patients ranged from 4 to 88 years with a mean age of 46.59 years in study of Chitturi et al 3 Manakkad et al found mean age of 47.14 years with age range of 2-85 years. 7 A lower mean age was observed in studies with larger volume of paediatric patients.…”

“…This finding is in accordance with studies of Chitturi et al 3 and Manakkad et al 7 The age of the patients ranged from 4 to 88 years with a mean age of 46.59 years in study of Chitturi et al 3 Manakkad et al found mean age of 47.14 years with age range of 2-85 years. 7 A lower mean age was observed in studies with larger volume of paediatric patients. 11 More than half the cases in our study was noted in 41-60 years age group, comparable to Sharma…”

“…A notably higher number of GI polypoidal lesions were found in males compared to females corroborating data from various studies. 3,[7][8][9] Majority (n=117, 78%) of the polypoidal lesions in our study were non-neoplastic. This finding is consistent with that of a study performed in Nepal by Gurung et al in which 70% GI polyps were nonneoplastic.…”

“…2 In contrast, neoplastic polypoidal lesions were more prevalent in studies performed by Manakkad et al in India and Mirzaie et al in Iran. 7,9 Polypoidal lesions with malignant potential are classified as neoplastic whereas non-neoplastic ones have none or lesser possibility of malignant transformation. 3 The presence or potential risk of malignancy in these polypoidal lesions is the key concern.…”

“…4 The size and site of the polyp and age of the patient are found to be significant risk factors for development of malignancy. [5][6][7] Histopathological examination is crucial as the biological behavior is dependent on its pathological nature.…”