Morphological Spectrum of Pediatric Central Nervous System Tumors- A seven year study from Central India

Gupta, Avinash; Bhopal, India Formerly Senior Resident Bmhrc

doi:10.18535/jmscr/v7i2.196

Cited by 1 publication

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References 8 publications

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“…Multiple retrospective studies and few prospective studies are available regarding clinical profile of paediatric brain tumours. Institutions in the different zones of the country has reported their clinical profiles of paediatric brain tumours which are very much similar [6][7][8][9][10].…”

Section: Clinical Profilementioning

confidence: 99%

Clinical Profile, Patterns of Care and Outcomes of Childhood CNS Tumours in India

Mullapally¹,

Dusi²,

Digumarti³

2023

Central Nervous System Tumors - Primary and Secondary

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Paediatric CNS tumours are the third most common childhood malignancy in India. They account for 14% of all cancers in the 1–14 years age group. There is dearth of adequate prospective or retrospective studies about patterns of care and outcomes. There is male preponderance. Primitive Neuro-ectodermal tumours (PNET) are the most common histology followed by astrocytoma and other gliomas among children from 0 to 19 years. Surgery, radiotherapy, and chemotherapy are the main modalities of treatment. Available data points to underutilisation of radiotherapy in clinical practice due to the fear of non-compliance. Paediatric CNS tumours outcomes are different from adult brain tumours due to their aggressive histology, variable clinical presentations, delay in diagnosis, etc. There is also shortage of adequate multidisciplinary paediatric neuro-oncology units in the country. Future directions include setting up more dedicated paediatric neuro-oncology units, implementation of new 2022 WHO classification by adopting molecular testing across different histology’s, use of better radiation technology to prevent long term neurocognitive and other late effects and survivorship clinics to monitor for late effects and rehabilitate the childhood cancer survivors and, perhaps a registry. These issues are discussed in detail in this chapter.

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Section: Clinical Profilementioning

confidence: 99%

Clinical Profile, Patterns of Care and Outcomes of Childhood CNS Tumours in India

Mullapally¹,

Dusi²,

Digumarti³

2023

Central Nervous System Tumors - Primary and Secondary

View full text Add to dashboard Cite

show abstract

Morphological Spectrum of Pediatric Central Nervous System Tumors- A seven year study from Central India

Abstract: Introduction: Tumors of the nervous system are important cause of cancer-related deaths in children. There are several reports regarding the epidemiology of CNS tumors in children in the Western literature but too few reports from India.

Cited by 1 publication

References 8 publications

Clinical Profile, Patterns of Care and Outcomes of Childhood CNS Tumours in India

Clinical Profile, Patterns of Care and Outcomes of Childhood CNS Tumours in India

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