Morphological changes in normal canine basilar arteries after transluminal angioplasty

Chávez, Luis Ángel Rodríguez; Takahashi, Akira; Yoshimoto, Takashi; Su, Chin Chang; Sugawara, Takayuki; Fujii, Yoshiaki

doi:10.1080/01616412.1990.11758592

Cited by 25 publications

(9 citation statements)

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“…The rabbit NLD runs through a bony canal into the nasal passages. 8,9 Because the rabbit has a nasolacrimal system similar to humans both structurally and histologically, a rabbit model was used to evaluate this procedure.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Histopathologic Effects of Balloon Dacryoplasty on the Rabbit Nasolacrimal Duct

Goldstein¹,

Katowitz²,

Syed³

2006

Journal of American Association for Pediatric Ophthalmology and

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Section: Discussionmentioning

confidence: 99%

“…Because rabbits have a nasolacrimal duct system structurally and histologically similar to humans, a rabbit model for balloon dacryoplasty was designed and tested. 8,9 METHODS Infant New Zealand rabbits were sedated with intramuscular ketamine (35 mg/kg) and zylazine (5 mg/kg) injections. Each rabbit weighed approximately 2 kg.…”

mentioning

confidence: 99%

The Histopathologic Effects of Balloon Dacryoplasty on the Rabbit Nasolacrimal Duct

Goldstein¹,

Katowitz²,

Syed³

2006

Journal of American Association for Pediatric Ophthalmology and

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“…3 There are reports of histopathological data obtained immediately after angioplasty that focused on arteries dilated to larger-than-normal diameters or on arteries that were contracted pharmacologically and then subjected to angioplasty. 2,13,19 Pathological changes noted in these reports included endothelial desquamation, compression of the tunica media, and stretching of the internal elastic lamina. Fracturing of the internal elastic lamina was limited to cases in which the artery was dilated to a diameter greater than its norm.…”

Section: Previous Studies Of Angioplastymentioning

confidence: 95%

Pathological effects of angioplasty on vasospastic carotid arteries in a rabbit model

Rl¹,

Wallace²,

Wj³

et al. 1995

Journal of Neurosurgery

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To define the pathological effects of angioplasty on vasospastic arteries, 36 rabbits underwent angiography and induction of vasospasm by placement of blood-filled (vasospasm groups) or empty (control group) silastic sheaths around the cervical carotid arteries. Two (Day 2) or 7 days (Day 7) later, angiography was repeated and one carotid artery in each animal was dilated by balloon angioplasty. The rabbits were sacrificed 1 day, 7 days, or 3 to 4 weeks after angioplasty. Significant vasospasm developed after placement of silastic sheaths with blood (mean reductions in diameter 39% +/- 6% at Day 2 and 48% +/- 5% at Day 7). Arterial narrowing was less apparent in the control groups at Day 2 (24% +/- 7%). Angioplasty performed on Day 2 significantly increased arterial diameters of vasospastic arteries (50% +/- 7%; p < 0.05) but not those of control arteries (10% +/- 6%, p > 0.05). Angioplasty performed on Day 7 increased the arterial diameters by a similar degree (47% +/- 13%, not significant). Arteries remained dilated after angioplasty, although there was significant vasospasm 7 days after angioplasty when angioplasty was performed on Day 2. Blinded, semiquantitative histopathological study of the arteries showed that 3 to 4 weeks after angioplasty, there was significant endothelial proliferation and a trend for thinning of the tunica media. There were no significant changes in control arteries subjected to angioplasty. Angioplasty was not associated with significant arterial fibrosis as measured by hydroxyproline content (analysis of variance). The increase in endothelial proliferation and decrease in the thickness of the tunica media suggest that, in the rabbit model, angioplasty damages endothelial and smooth-muscle cells. This may be the basis for the observation that vasospastic arteries do not reconstrict after angioplasty.

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“…These changes returned to normal in 7 days. Similarly, another group [23] histologically studied canine basilar arteries that had a 30% dilation via balloon angioplasty. They demonstrated denudation of endothelial cells, significant deposition of fibrin, and like Yamamoto et al [22] a stretching and focal dehiscence of the internal elastic lamina and altered myocytes in the media.…”

Section: Pathophysiology Of Balloon Angioplastymentioning

confidence: 99%

Delayed progressive bilateral supraclinoid internal carotid artery stenosis in a patient with a ruptured basilar artery aneurysm

Safain

Malek

2015

Journal of Clinical Neuroscience

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Morphological changes in normal canine basilar arteries after transluminal angioplasty

Cited by 25 publications

References 0 publications

The Histopathologic Effects of Balloon Dacryoplasty on the Rabbit Nasolacrimal Duct

The Histopathologic Effects of Balloon Dacryoplasty on the Rabbit Nasolacrimal Duct

Pathological effects of angioplasty on vasospastic carotid arteries in a rabbit model

Delayed progressive bilateral supraclinoid internal carotid artery stenosis in a patient with a ruptured basilar artery aneurysm

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