1998
DOI: 10.1007/s00276-998-0171-6
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Morphologic and histologic study of the ligamentum flavum in the thoraco-lumbar region

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Cited by 16 publications
(23 citation statements)
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“…The clinical significance of pathologic changes in the LF has been examined previously (Markiewitz et al, 1996;Viejo-Fuertes et al, 1998). Spinal canal imaging is able not only to diagnose rare disorders but also to aid the development of new surgical techniques.…”
Section: Discussionmentioning
confidence: 99%
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“…The clinical significance of pathologic changes in the LF has been examined previously (Markiewitz et al, 1996;Viejo-Fuertes et al, 1998). Spinal canal imaging is able not only to diagnose rare disorders but also to aid the development of new surgical techniques.…”
Section: Discussionmentioning
confidence: 99%
“…The deep and superficial layers of the LF adhere to each other firmly (Viejo-Fuertes et al, 1998). The exact function of the LF is unknown, but it is a connective tissue and thought to affect the intrinsic stability of the spine, control to intervertebral movement, and maintenance of a smooth surface of the posterior dural sac (Winkler et al, 2007).…”
Section: Introductionmentioning
confidence: 99%
“…Histologic studies have found that fibrocartilaginous transformation provoked by collagen proliferation and ossification can lead to LF thickening. 6,12 Age-related fibrosis or decrease in the elastin-tocollagen ratio, in combination with biomechanical stress, has been reported to lead to thickening of the LF. [5][6][7] Pathologic studies have revealed leakage of inflammatory cytokines from degenerating facet joints, implicating these molecules as causes of both LF thickening and pain generation in the adjacent nerve fibers.…”
Section: Discussionmentioning
confidence: 99%
“…The LF has the highest elastincollagen ratio of the spinal ligaments (Yong-Hing et al, 1976;Viejo-Fuertes et al, 1998). It has been shown to be comprised of 50% to 80% elastin fibres, with a 2:1 elastin to collagen ratio, with collagen fibers exhibiting no favored orientation (Nachemson et al, 1968), compared to the other primary ligaments which only contain 5% to 30% elastin fibres (Pintar, 1986).…”
Section: Ligamentum Flavummentioning
confidence: 99%