Morphogenesis of the spinal canal, normal and stenotic

Abstract

The closest formative developmental dependence of the axial skeleton upon the morphogenesis of the intraspinal nervous structures is reflected in the roentgen features of the individual vertebrae as well as of the vertebral column in its entirety. The vertebroneural developmental events are characterized by a steady relative decrease in size of the nervous structures (the first to be laid down and huge in the embryonic period) under a corresponding increase in size of the skeletogenic tissues. There exists experimental evidence that the maintenance of the necessary developmental balance between the two tissues, the bony and the skeletogenic, is a function of the nervous substance. The tight spinal canal appears to result from a failure of the latter neural function leading to overgrowth of the bony structures, viz., to massive vertebrae and laminae encroaching upon the neural contents. Morphogenesis of the normal and tight lumbar spinal canal is discussed with special reference to the developmental interrelations between the cauda equina complex and the lumbar vertebrae.

Three‐dimensional sonographic evaluation of the fetal lumbar spinal canal

“…The development of the lumbar vertebral is of clinical significance. A small vertebral canal is considered to be one of the causes for back pain in later life (Roth et al. 1976; O’Rahilly et al.…”

“…The development of the lumbar vertebral is of clinical significance. A small vertebral canal is considered to be one of the causes for back pain in later life (Roth et al 1976;O'Rahilly et al 1980;Porter et al 1980), but these syndromes are multifactorial. In a small spinal canal, disc lesions, osteophytes or segmental instability cause earlier compression of neural structures with a concomitant increase in the risk of symptomatic disk lesion (Mooney, 1983;Porter et al 1980).…”

“…1994). Defective development at this stage is of clinical significance as a small lumbar vertebral canal is considered to be a significant risk factor for back pain syndromes in adulthood (Roth et al. 1976; Mooney, 1983; Papp & Porter, 1994).…”

“…Importantly, the cross-sectional area of the mid-lumbar canal has already reached its adult size by the age of 1 year (O'Rahilly et al 1980;. Defective development at this stage is of clinical significance as a small lumbar vertebral canal is considered to be a significant risk factor for back pain syndromes in adulthood (Roth et al 1976;Mooney, 1983;.…”

Degenerazione discale, spondilosi e artrosi: Proposta di meccanismo patologico sulla base dell'approccio neuroradiologico

“…rallentamento dell'accrescimento neurospinale (che si riflette nello spostamento craniale dei gangli spinali nei rispettivi forami intervertebrali; B, F), raffronta figura 4A, C; E). I recessi ventrolaterali dei forami vertebrali trilobati costituiscono delle «impronte» delle radici nervose e(o dei gangli[51].Figure 6Neurovertebral developmental dynamics shown in L5, SI vertebrae ,from the early embryonic kyphosis attributed to the rapid growth of the dorsally situated primordia of the central nervous system3 (A) to lumbosacral lordosis related to slowing down of the spinal neural growth (reflected in cranial shift of the spinal ganglia within their intervertebral foramina [B ) F) camp. figure 4A, C, E)}.…”