Morinda citrifolia Plays a Central Role in the Primary Prevention of Mitochondrial-dependent Degenerative Disorders

Caramel, Simone; Marchionni, Marco; Stagnaro, Sergio

doi:10.7314/apjcp.2015.16.4.1675

Cited by 8 publications

(7 citation statements)

References 9 publications

(8 reference statements)

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“…In addition to the antioxidant properties present in the fruit juice noni, Caramel, Stagnaro, and Marchionni () conducted in vivo clinical trials to evaluate several quantitative and qualitative parameters regarding the latency and duration of different gastric reflexes in seven healthy individuals using the method of Auscultatory Percussion of the stomach. Confirmation of antioxidant activity in the juice revealed other properties intrinsic to this activity, such as reduction/normalization of the tissue acidosis, improvement in acid–base balance in the blood, and ameliorating/normalizing the mitochondrial redox activity as well as the tissue oxygenation.…”

Section: Phytotherapic Propertiesmentioning

confidence: 99%

Properties and Applications of Morinda citrifolia (Noni): A Review

Almeida

Oliveira

Hotza

2019

Comp Rev Food Sci Food Safe

110

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Morinda citrifolia commonly known as noni is a perennial plant originating in Southeast Asia, consumed over 2000 years. Due to its versatility of adaptation and use of the structures of the plant for different therapeutic purposes, noni attracted the attention of researchers from the pharmaceutical and food industry. Chemical and nutritional analyzes already performed in M. citrifolia reveal the existence of more than 200 phytochemical substances with bioactive properties such as acids, alcohols, phenols, saccharides, anthraquinones, carotenoids, esters, triterpenoids, flavonoids, glycosides, lactones, iridoids, ketones, lactones, lignans, nucleosides, triterpenides, sterols, and aromatic compounds. The high nutritional value of M. citrifolia may induce therapeutic effects, including antimicrobial and antioxidant properties. The main industrial products from this plant are beverages (juice drinks), powders (from dried fruits), oil (from seeds), and leaf powders. Biological and phytotherapeutic applications of M. citrifolia are promising, but more extensive studies are still required. Thus, this review aims to gather updated and comprehensive information on Morinda citrifolia, discussing its traditional use, biochemical, phytotherapics, and toxicological properties, as well as the recent advances in the processing and standardization of products derived from noni fruit.

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Section: Phytotherapic Propertiesmentioning

confidence: 99%

Properties and Applications of Morinda citrifolia (Noni): A Review

Almeida

Oliveira

Hotza

2019

Comp Rev Food Sci Food Safe

110

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“…The antioxidant properties of noni fruit juice in humans involve decreased tissue acidosis, acid–basic balance, improvement of mitochondrial redox activity, increased tissue oxygenation and improvement of the body metabolism as a whole (Caramel et al , ). In smokers, TNJ® ingestion had antioxidant effects, reducing the plasma levels of superoxide anion (SAR) and lipid hydroperoxide (LOOH).…”

Section: Antioxidant Activitymentioning

confidence: 99%

One Plant, Many Uses: A Review of the Pharmacological Applications of Morinda citrifolia

Torres

Magalhães

Mondêgo-Oliveira

et al. 2017

Phytotherapy Research

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Morinda citrifolia, also known as noni, is commonly used in popular medicine in Brazil. Many parts of the noni tree are utilized in such practices, including the roots, leaves and seeds. Through a search of online databases, the present article reviews 92 research studies on the biological actions of M. citrifolia. The paper will discuss the therapeutic effects of noni and its compounds in a variety of forms of presentation, focusing on studies that support its traditional use. A large and diverse number of properties were identified, which were divided into immunostimulatory, antitumor, antidiabetic, anti-obesity, antibacterial and anti-septic, antifungal, antiviral, leishmanicidal, antiinflammatory, antinociceptive and analgesic, antioxidant, neuroprotective, wound healing, antiallergic, antiangiogenic, antiemetic and anti-nausea, anti-gastric ulcer and oesophagitis, anthelmintic, antimutagenic, antipsychotic, anxiolytic, photoprotective, anti-wrinkle and periodontal tissue regeneration activities. While it was concluded that although M. citrifolia is widely and successfully used for the treatment or prevention of various diseases, it should be consumed carefully, and only after exhaustive studies into its chemical constituents and mechanisms of action, both in in vitro and in vivo models, as well as clinical trials. Copyright © 2017 John Wiley & Sons, Ltd.

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“…There is a class of treatments (i.e., green therapy) that, if adequately combined and integrated, should allow to make a pathological IRR, like the IRR of epilepsy, a residual factor (Stagnaro, 2004b;Marchionni et al, 2013aMarchionni et al, , 2013bMarchionni et al, , 2014Stagnaro and Caramel, 2011b, 2012a, 2012b, 2013a, 2013b, 2013c, 2013dCaramel et al, 2014). To make a risk residual does not mean to remove it completely, but to reduce it to a minimum, i.e.…”

Section: Inherited Real Risk Of Epilepsy: Qbs Diagnosismentioning

confidence: 99%

“…This strengthens and confirms the existing theories on wave genomics, according to Peter Gariaev (1994), and on genetic/genomic reversibility of nuclear and mitochondrial DNA, and especially the principle of Recursive Genome Function introduced by the American crossdisciplinary scientist and technologist Andras Pellionisz (Stagnaro and Caramel, 2011a). Clinical and experimental evidence of success in healing many pathological IRRs, among which the IRR of epilepsy, comes from the application of millimeter waves in 'Body Resonance Recording' (BRR) mode (Cem-Tech, now Ak-Tom) , from quantum therapy with sodium bicarbonate (Stagnaro, 2015a) (taking advantage of the extraordinary possibilities provided by quantum medicine combined with frequential information acquired by ad hoc substances, where water acts in harmony with the principle of water information memory), from noni juice (Caramel et al, 2015) and from sulfurous water .…”

Section: Inherited Real Risk Of Epilepsy: Qbs Diagnosismentioning

confidence: 99%

Integrated Quantum Therapy in an Epileptic Child after 13 Years of Inherited Real Risk of Epilepsy in Evolution: A Case Study

2016

Self Cite

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The comprehension of the pathogenesis of epilepsy finds a new impulse in studies on non-linear dynamics of EEG signals and in the growing genetic molecular evidence of the mitochondrial origin of this disease. These data are consistent with the information known by Quantum Biophysical Semeiotics that clinically investigates microcirculation both on a functional (i.e. by studying its non-linear dynamics), and on a structural viewpoint. Microcirculatory dysfunctions reflect those of a genetically altered mit-DNA and of a functional mitochondrial cytopathy known as Congenital Acidosic Enzyme-Metabolic Histangiopathy, originating from this mutation and which is particularly intense both in patients with epilepsy and in those with Inherited Real Risk of epilepsy. Preclinical diagnosis of Inherited Real Risk of epilepsy presents the opportunity to examine subjects with a predisposition to this disease since birth in order to perform an efficient pre-primary and primary prevention. In our case report, an integrated quantum therapy applied to a child with Inherited Real Risk of epilepsy in strong evolution provides encouraging satisfactory results.

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Morinda citrifolia Plays a Central Role in the Primary Prevention of Mitochondrial-dependent Degenerative Disorders

Cited by 8 publications

References 9 publications

Properties and Applications of Morinda citrifolia (Noni): A Review

Properties and Applications of Morinda citrifolia (Noni): A Review

One Plant, Many Uses: A Review of the Pharmacological Applications of Morinda citrifolia

Integrated Quantum Therapy in an Epileptic Child after 13 Years of Inherited Real Risk of Epilepsy in Evolution: A Case Study

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